2024 ISMRM and ISMRT Annual Meeting and Exhibition
4 May 2024 – 9 May 2024 · Singapore, Singapore
2181 ISMRM Abstract

Automatic detection and measurement of WM lesions in MS patients using MR-STAT and a self-supervised bivariate Gaussian probabilistic model

Accepted
Martin B Schilder 1, Stefano Mandija1, Sarah M Jacobs2, Jordi P Kleinloog1, Hanna Liu1, Oscar van der Heide1, Vera Keil3, Evert-Jan P Vonken4, Jan Willem Dankbaar4, Jeroen Hendrikse4, Cornelis A van den Berg1, Anja van der Kolk4,5, Alessandro A Sbrizzi1
1Computational Imaging Group for MR Therapy and Diagnostics, University Medical Center Utrecht, Utrecht, Netherlands
2Department of Radiology and Nuclear Medicine, University Medical Center Utrecht, Utrecht, Netherlands
3Department of Radiology, Amsterdam UMC, Amsterdam, Netherlands
4Department of Radiotherapy, University Medical Center Utrecht, Utrecht, Netherlands
5Department of Medical Imaging, Nijmegen, Netherlands
Presenting Author: Martin B Schilder
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References

1. Wattjes MP, Ciccarelli O, Reich DS, et al. 2021 MAGNIMS–CMSC–NAIMS consensus recommendations on the use of MRI in patients with multiple sclerosis. Lancet Neurol. 2021;20(8):653-670. doi:10.1016/S1474-4422(21)00095-8 2. Piredda GF, Hilbert T, Granziera C, et al. Quantitative brain relaxation atlases for personalized detection and characterization of brain pathology. Magn Reson Med. 2020;83(1):337-351. doi:10.1002/mrm.27927 3. Ravano V, Caneschi S, Krasensky J, et al. Normative brain atlas of T2/T1 relaxometry ratio for detection of microstructural pathology. In: Proc. Intl. Soc. Mag. Reson. Med. 31 (2023). ; 2023. [doi]
2. Sbrizzi A, Heide O van der, Cloos M, et al. Fast quantitative MRI as a nonlinear tomography problem. Magn Reson Imaging. 2018;46:56-63. doi:10.1016/j.mri.2017.10.015 5. Kleinloog JPD, Mandija S, D’Agata F, et al. Synthetic MRI with Magnetic Resonance Spin TomogrAphy in Time-Domain (MR-STAT): Results from a Prospective Cross-Sectional Clinical Trial. J Magn Reson Imaging. 2023;57(5):1451-1461. doi:https://doi.org/10.1002/jmri.28425 6. Liu H, van der Heide O, Mandija S, van den Berg CAT, Sbrizzi A. Acceleration Strategies for MR-STAT: Achieving High-Resolution Reconstructions on a Desktop PC Within 3 Minutes. IEEE Trans Med Imaging. 2022;41(10):2681-2692. doi:10.1109/TMI.2022.3168436 7. McCarthy P. FSLeyes. Published online June 13, 2023. doi:10.5281/ZENODO.8033457 8. Manjón J V., Romero JE, Vivo-Hernando R, et al. vol2Brain: A New Online Pipeline for Whole Brain MRI Analysis. Front Neuroinform. 2022;16. doi:10.3389/fninf.2022.862805 9. Okubo G, Okada T, Yamamoto A, et al. Relationship between aging and T 1 relaxation time in deep gray matter: A voxel-based analysis. J Magn Reson Imaging. 2017;46(3):724-731. doi:10.1002/jmri.25590 10. Badve C, Yu A, Rogers M, et al. Simultaneous T1 and T2 Brain Relaxometry in Asymptomatic Volunteers Using Magnetic Resonance Fingerprinting. Tomography. 2015;1(2):136-144. doi:10.18383/j.tom.2015.00166 11. Liu H, Van Der Heide O, Versteeg E, et al. A three-dimensional MR-STAT protocol for high-resolution multi-parametric quantitative MRI. NMR Biomed. 2023;IN PRESS [doi]

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