Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026
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570-04-189.
Liver PDFF and water T1 and T2 mapping in a single breath hold using multi-echo phase-cycled bSSFP
Impact: The proposed technique allows for fast and accurate fat-fraction measurements and water-specific T1 & T2 mapping in the liver, potentially providing a valuable clinical tool for the diagnosis and monitoring of liver disease, which currently affects 25% of the worldwide population.
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570-04-190.
Robust free breathing liver diffusion-weighted imaging
Impact: The proposed algorithm for
slice alignment and motion-induced signal loss mitigation enables robust free
breathing liver DWI.
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570-04-191.
Assessment of Liver Fibrosis: Comparison of Gd-EOB-DTPA-enhanced T1 mapping and Diffusion Kurtosis Imaging
Impact: Diffusion Kurtosis Imaging offers similar diagnostic performance to Gd-EOB-DTPA-enhanced T1 mapping in staging liver fibrosis
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570-04-192.
Restricted Spectrum Imaging for Diagnosis of High-Risk Metabolic Dysfunction-Associated Steatohepatitis
Impact: RSI provides clinicians with a novel quantitative MRI biomarker for high-risk MASH diagnosis, potentially reducing reliance on invasive liver biopsies. This multi-compartmental approach enables investigation of hepatic microstructural changes and may guide treatment stratification in high-risk MASH patients.
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570-04-193.
Susceptibility Separation Reveals Hepatic Paramagnetic and Diamagnetic Alterations in Type 2 Diabetes Mellitus
Impact: Susceptibility
separation QSM enables disentangling hepatic paramagnetic and diamagnetic
components, revealing diamagnetic susceptibility reduction in T2DM patients.
This technique provides a new biomarker to monitor metabolic liver alterations.
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570-04-194.
Inter-patient heterogeneity of T1 and T2 relaxation times and visibility of liver metastases treated on an MR-linac
Impact: Our
approach demonstrated that imaging contrast between liver metastases
and liver can be improved with an average[range] of 142%[17%-3484%] without a
contrast agent. The increased contrast can facilitate accurate delineations and
online guidance for improved MRI-guided stereotactic body radiation therapy.
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570-04-195.
In-vivo Multiparametric Imaging and PDFF in the Liver at 0.1 T: Initial Results
Impact: We demonstrated
the feasibility of water-fat separation and multiparametric imaging in the
liver at very low field (≤0.1T). Once optimized and validated, these approaches
could enable early MASLD diagnosis and intervention in underserved communities
where prevalence is rapidly increasing.
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570-04-196.
Accelerated Water-Specific T1 Mapping of the Liver Using Multiband Chemical-Shift-Encoded MOLLI
Impact: Multiband cseMOLLI enables rapid,
water-specific T1 mapping of the entire liver in two breath-holds. By
increasing spatial coverage without lengthening scan time, this technique
supports comprehensive, quantitative assessment for clinical and research
applications in diffuse liver disease.
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570-04-197.
Hepatosplenic Stiffness in Pediatric Cystic Fibrosis: Cross-Validation of MR Elastography and Ultrasound Elastography
Impact: MR elastography differentiated pediatric
cystic fibrosis patients with hepatic fibrosis or steatosis from those without
liver involvement, based on liver and spleen stiffness. Findings were validated
by ultrasound-based time-harmonic elastography and transient shear-wave elastography,
enabling comprehensive non-invasive hepatosplenic stiffness evaluation.
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© 2026 International Society for Magnetic Resonance in Medicine