Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition - Next-Level Pediatric MRI: Technical Advances To Image Children Better

Next-Level Pediatric MRI: Technical Advances To Image Children Better

Oral

Pediatrics

Monday, 11 May 2026

Hall 1B

13:50 - 15:40

Moderators: Katrin Koziel & James Holmes

Session Number: 302-03

No CME/CE Credit

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This session showcases technical advances in MRI at all levels from scan acquisition to sequence design to post-processing and analysis designed to improve how we image children. Topics cover a range of anatomies (brain, cardiac, lung, abdomen) and a range of challenges to be addressed.

Skill Level: Intermediate

13:50		302-03-001. Highly Accelerated Navigator-Gated 4D MUSIC: Feasibility in Pediatric Congenital Heart Disease Xiaodong Zhong, Kevin Whitehead, Shu-Fu Shih, Fei Han, Ning Jin, Robert Gagnon, Robert Sellers, Xiaoming Bi, Mark Fogel, J. Paul Finn University of California Los Angeles, Los Angeles, United States of America Impact: Highly accelerated ferumoxytol-enhanced, navigator-gated 4D MUSIC is feasible in children with congenital heart disease and has the potential to greatly improve workflow and minimize the required duration of anesthesia.
14:01		302-03-002. Fetal Cardiac MRI to Improve the Diagnosis of Congenital Heart Disease: the FUTURE 2.0 study Roos de Lange, Anneloes Bohte, Sally-Ann Clur, Zina Fejzic, Stefan Frerich, Suzanne Gommers, Willem Helbing, Ward Y Vanagt, Annelies van der Hulst, Arend van Deutekom, Joost van Schuppen, Hans Breur, Pim van Ooij University Medical Center Utrecht, Utrecht, Netherlands Impact: Fetal black-blood CMR has the potential to enhance prenatal CHD diagnosis by complementing and overcoming the limitations of echocardiography, enabling more accurate parental counselling and improved neonatal outcomes.
14:12		302-03-003. Simultaneous 3D structural-functional assessment of pediatric lung at 0.55T using bSTAR Xin Miao, Nam Lee, Eamon Doyle, Ziwei Zhao, Sophia Cui, Narayan Iyer, Roberta Kato, Krishna Nayak Children's Hospital Los Angeles, Los Angeles, United States of America Impact: This study demonstrated high-resolution 3D lung structural imaging and ventilation mapping can be achieved in a single 8-13-minute free-breathing acquisition using 0.55T bSTAR. This technique enables reliable simultaneous structural–functional assessment in pediatric lung patients without radiation or contrast administration.
14:23		302-03-004. Ultra-Low-Field MRI as a Tool for Measuring Brain Development in LMICs: Feasibility, Validity and Clinical Relevance Layla Bradford, Jessica Ringshaw, Thokozile Malaba, Niall Bourke, Catherine Wedderburn, Steven Williams, Sean Deoni, Lauren Davel, Helen Reynolds, Angela Colbers, Duolao Wang, Saye Khoo, Landon Myer, Kirsten Donald Neuroscience Institute, University of Cape Town, South Africa Impact: This cross-validation study validates ultra-low-field MRI as a feasible and biologically meaningful tool for assessing early brain development in children in low-resource settings. The approach enables scalable neuroimaging of vulnerable populations and supports future global surveillance of neurodevelopmental risk.
14:34		302-03-005. Prospective Head-Motion Correction Improves the Quality of Anatomical Brain MRI in Naturally Sleeping Infants Zakaria Zariry, Nathalie Richard, Robert Frost, Sara Cabet, Franck Lamberton, Andre van der Kouwe, Pierre-Aurelien BEURIAT, Marine Gautier-Martins, Valentine Lecuyer, Lena Durieux, James Bonaiuto, Holly Rayson, Bassem Hiba Institut des Sciences Cognitives Marc Jeannerod (ISC MJ) - CNRS UMR5229, Bron, France Impact: Prospective motion correction enhances image quality in naturally sleeping infants’ brain MRI, yielding sharper images and more reliable cortical morphometry, thereby improving the validity of early-life neuroimaging biomarkers and fostering standardized, motion-aware, sedation-free pediatric imaging protocols.
14:45		302-03-006. Cortical laminar microstructure in children using multi-shell diffusion MRI with isotropic submillimeter resolution Ziqin Zhang, Wentao Wu, Kaitlyn Woods, Minhui Ouyang, Hao Huang Children's Hospital of Philadelphia, Philadelphia, United States of America Impact: This study offers insight into laminar cortical cytoarchitecture during childhood for the first time with cutting-edge sub-millimeter diffusion MRI. A novel cortical laminar microstructure measurement pipeline was developed for high-precision measures of cortical microstructure by maximally mitigating partial volume effects.
15:07		302-03-008. 3D Distortion-Free Fetal Brain R2* Mapping Using Multi-Oriented Multi-Echo Radial FLASH and Slice-to-Volume Reconstruction Haykel Snoussi, Daniel Mackner, Guanxiong Luo, Hongli Fan, Patricia Grant, Edward Yang, Martin Uecker, Ali Gholipour, Simon Warfield, Xiaoqing Wang Boston Children's Hospital and Harvard Medical School, Boston, United States of America Impact: Our method enables distortion-free, isotropic fetal brain R2* mapping through multi-oriented multi-echo radial FLASH acquisitions combined with model-based and motion-corrected slice-to-volume reconstruction. This approach overcomes the low-resolution and geometric distortion artifacts commonly observed in EPI-based techniques.
15:18		302-03-009. AI-guided autonomous fetal MRI Sara Neves Silva, Jordina Aviles Verdera, Alena Uus, Aysha Luis, Susanne Schulz-Heise, Sarah McElroy, Raphael Tomi-Tricot, Lisa Story, Jo Hajnal, MARY RUTHERFORD, Jana Hutter King's College London, London, United Kingdom Impact: A self-guided MRI examination was successfully developed, eliminating the need for specialist planning or offline processing and enabling future clinical translation of advanced fetal MRI techniques.
15:29		302-03-010. Towards Motion-Robust, High-SNR Free-Breathing PDFF Mapping: Evaluation in Vertebral Bone Marrow, Paraspinal Muscle, Liver Utsav Shrestha, Nathan Roberts, Jiayi Tang, Amirhossein Roshanshad, Felix Schön, Julius Heidenreich, Arnaud Guidon, Scott Reeder, Diego Hernando University of Wisconsin - Madison, Madison, United States of America Impact: Free-breathing proton-density fat-fraction (PDFF) mapping with high isotropic resolution, SNR, and motion robustness improves image quality in children and the elderly, individuals unable to perform breath-holds due to illness or limited compliance, and enhances reliable PDFF assessment of heterogeneous tissues.