Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026

Oral

Prostate MRI: Methodological Developments

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Prostate MRI: Methodological Developments
Oral
Body
Thursday, 14 May 2026
Hall 1B
13:40 - 15:30
Moderators: Yannik Ott
Session Number: 602-02
No CME/CE Credit
This session includes presentations covering the use of MRI in prostate cancer and prostatic diseases.
Skill Level: Intermediate

13:40 Figure 602-02-001.  Short TE From a Nonlinear Gradient Coil Improves Image Quality and Lesion Conspicuity of Prostate DWI
Summa Cum Laude
Horace Zhang, Nahla Elsaid, Terence Nixon, Andrew Dewdney, Dana Peters, Jeffrey Weinreb, Preston Sprenkle, R. Todd Constable, Gigi Galiana
Yale University, New Haven, United States of America
Impact: The proposed nonlinear gradient coil provides an accessible and cost-effective alternative to whole-body strong-gradient systems, significantly boosting prostate DWI quality and cancer lesion conspicuity on conventional MRI scanners.
13:51 Figure 602-02-002.  Diffusion-Relaxation Correlation Spectroscopic MRI for Characterizing Prostate Cancer versus Whole-Mount Histopathology
Summa Cum Laude AMPC Selected
Elif Aygun, Zhaohuan Zhang, Steven Raman, Robert Reiter, Anthony Sisk, KyungHyun Sung, Holden Wu
David Geffen School of Medicine, University of California Los Angeles, Los Angeles, United States of America
Impact: Prostate microstructure parameters obtained from diffusion-relaxation correlation spectroscopic MRI (DR-CSI) demonstrated differences between indolent and clinically significant prostate cancer. DR-CSI has the potential to improve the characterization of prostate cancer.
14:02 Figure 602-02-003.  Water-exchange DCE-MRI for Prostate Lesions: Complementary Value of Kio and Ktrans in Stratifying Lesions and Guiding Targete
Da Li, chao wang, ruiliang bai, Lei Zhang, xiaoqian xu, lei tian, Sicong Wang, Fenghai Liu
Cangzhou Central Hospital Affiliated to Hebei Medical University, Cangzhou, China
Impact: Water-exchange DCE-MRI yields complementary biomarkers for prostate lesions: Ktrans separates lesion categories, while Kio correlates with PSA density and consistently highlights clinically significant cores, supporting precision MRI-targeted biopsy and decision-making.
14:13 Figure 602-02-004.  MRI-Guided Transgluteal Prostate Biopsy at 0.55T: Clinical Experience
Vikas Gulani, Yun Jiang, Tejinder Kaur, John Wei, Shane Wells, Elaine Caoili
University of Michigan, Ann Arbor, United States of America
Impact: We share experience with MRI-guided percutaneous transgluteal biopsy technique using a wide bore, 0.55T scanner, showing this is a clinically feasible and highly accurate approach with high clinical impact, for sampling prostatic cancer suspicious lesions in patients.
14:24 Figure 602-02-005.  Decoding the Determinants of Prostate MRI Quality: Multicenter Analysis and an AI Model for Early Prediction of Image Failure
jeff brender, Mitsuki Ota, Nathan Nguyen, Joshua Ford, Shun Kishimoto, Murali Krishna, Peter Choyke, Baris Turkbey
Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, United States of America
Impact: The deep learning approach enables early detection of potential quality issues during prostate MRI, allowing corrective actions before completing the full protocol. The model's strong generalization across sites suggests broad clinical applicability, potentially reducing repeat scans and improving diagnostic accuracy.
14:35 Figure 602-02-006.  Deep Learning-based Automatic Oblique Scan Angulation for Axial Prostate MRI
Robert Grimm, Robin Hoepp, Tristan Rauhut, Cornelius Jacob, Guillaume Chabin, Heinrich von Busch, Florian Knoll, Sohrab Mirak, Leonardo BIttencourt
Research & Clinical Translation, Magnetic Resonance, Siemens Healthineers AG, Erlangen, Germany
Impact: An optimal scan orientation for axial prostate MRI scans, perpendicular to the anterior rectal, is automatically computed from sagittal localizer images. This helps streamlining the examination and can reduce inter-operator variability.
14:46 Figure 602-02-007.  Deep Learning-Based Detection of Clinically Significant Prostate Cancer from Degraded MRI
Patricia Johnson, Tarun Dutt, Angela Tong, Luke Ginocchio, Lavanya Umapathy, Sumit Chopra, Daniel Sodickson, Hersh Chandarana
New York University Grossman School of Medicine, New York, United States of America
Impact: AI maintained prostate cancer detection accuracy despite degraded MRI quality, demonstrating that diagnostic performance is not constrained by traditional image standards. These findings could enable faster, lower-cost MRI protocols and open new avenues for AI-first imaging and screening.
14:57 Figure 602-02-008.  Deep Learning-Based Detection of Extraprostatic Extension of Prostate Cancer on bpMRI compared to Readers on bpMRI and mpMRI
Angela Tong, Alexander Daniels, Luke Ginocchio, Tarun Dutt, Lavanya Umapathy, Sumit Chopra, Daniel Sodickson, Hersh Chandarana, Patricia Johnson
NYU Grossman School of Medicine, New York, United States of America
Impact: Deep learning algorithms can identify extraprostatic extension on bpMRI with high sensitivity and accuracy, which may be applied to optimizing management or serving as a decision maker at the scanner level to tailor protocols to patients’ needs.
15:08 Figure 602-02-009.  Aggressive Tumor Fraction as a Biomarker for Prostate Cancer Progression: Risk Assessment of Active Surveillance Patients
Ahmad Algohary, Veronica Wallaengen, Adrian Breto, Noah Lowry, Arpita Dutta, Nicolas Stoll, Sandra Gaston, Alan Pollack, Sanoj Punnen, Radka Stoyanova
University of Miami, Miami, United States of America
Impact: The Habitat Risk Score–derived Aggressive Tumor Fraction (ATF) quantifies intratumoral heterogeneity and predicts rapid prostate cancer progression. Incorporating ATF into a composite risk model improves active-surveillance patient stratification, enabling earlier intervention for high-risk individuals while reducing overtreatment of indolent disease.

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