Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026

Digital Poster

Quantitative Applications in Body MRI: In Numbers We Trust

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Quantitative Applications in Body MRI: In Numbers We Trust
Digital Poster
Body
Tuesday, 12 May 2026
Digital Posters Row G
09:15 - 10:10
Session Number: 466-02
No CME/CE Credit
This session includes presentations that utilize quantitative imaging and related biomarkers in body applications.
Skill Level: Intermediate

  Figure 466-02-001.  Research on Quantitative MR in the Evaluation of Liver Function and Prediction of the First Decompensation Event in Patients
Jie Zou, Yanli Jiang, Fengxian Fan, Pin Yang, Jing Zhang, Kai AI
Department of Magnetic Resonance, Lanzhou, China
Impact: This non-invasive MR model, utilizing T1post-20min and T1rho, enables accurate liver function assessment and early prediction of decompensation in high-risk CHB patients, guiding timely clinical intervention.
  Figure 466-02-002.  Characterization of peri-renal adipose tissue T2* and PDFF: scanner vendor reproducibility & scan-rescan repeatability on 3T
Markus Henningsson, Allie Schneider, Ella Jones, Matthew Robson, Carolina Fernandes
Perspectum, Oxford, United Kingdom
Impact: Our findings may support using peri-renal fat T2* and PDFF to measure abdominal brown adipose tissue repeatably and reproducibly. This could help elucidate pathophysiological mechanisms of obesity-induced kidney disease and supports use of MRI in clinical trials of obesity-targeting interventions.
  Figure 466-02-003.  Using a Respiratory Cushion in Renal Quantitative Susceptibility Mapping: A Way to Achieve High-Resolution Analysis?
Matthias Georg Deitermann, Birte Sehlmeyer, Mohamed Ali Goundi, Hans-Joerg Wittsack, Alexandra Ljimani, Anja Müller-Lutz, Eric Bechler
Medical Faculty, Heinrich Heine University Düsseldorf (DE), Düsseldorf, Germany
Impact: This work demonstrates the feasibility of acquiring renal quantitative susceptibility mapping (QSM) during free-breathing while controlling acquisition time frames with a respiratory cushion. The free- breathing outcomes matched breath-hold results while enabling higher image resolution.
  Figure 466-02-004.  Profiling Lipid Composition from Multi-Gradient Echo MRI – Preliminary Evaluation Using Fat Models, Phantoms and In vivo Data
Ashiqur Rahman, Nakul Gupta, Aaryani Tipirneni-Sajja
University of Houston, Houston, United States of America
Impact: This work advances non-invasive profiling of tissue fatty acid composition, extending MRI beyond total fat quantification toward detailed compositional lipid mapping.
  Figure 466-02-005.  Synthetic DWI with contrast synthesis and T1/T2 estimates may improve PI RADS 3 discrimination and reduce unneeded biopsies
Yu Ueda, Tsutomu Tamada, Atsushi Higaki, Kazunori Moriya, Shigeru Shibata, Makoto Obara, Masami Yoneyama, Marc Van Cauteren
Philips Japan, Tokyo, Japan
Impact: With only a 90-second extension, the modified Synthetic DWI enables contrast synthesis and reliable T1/T2 estimates, supporting improved discrimination in PI‑RADS 3 lesions (T2 shows less overlap than ADC). This suggests potential to reduce unnecessary biopsies in prostate cancer care.
  Figure 466-02-006.  Multiparametric MRI combined with machine learning algorithm for Evaluating Disease Progression in Rats with NASH
jiayi jiang, songying pi, Yaqin Zhang
The fifth Affiliated Hospital, Sun Yat-Sen University, zhuhai, China
Impact: This study demonstrates that multiparametric MRI integrated with machine learning enables accurate, non-invasive staging of NASH, offering a translational imaging framework that may guide diagnosis, monitor therapeutic response, and inspire further exploration of quantitative MRI biomarkers in metabolic liver disease.
  Figure 466-02-007.  Predicting esophageal cancer response to neoadjuvant therapy with diffusion MRI
Victoria Joppin, Laura Haefliger, Camille Noirot, Jean-Baptiste LEDOUX, Styliana Mantziari, Markus Schäfer, Fulvia Serra, Christine Sempoux, Naik Vietti-Violi, Clarisse Dromain, Ileana Jelescu
Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland
Impact: Diffusion MRI may enable early, non-invasive prediction of therapeutic response in esophageal cancer, supporting a potential “watch-and-wait” strategy for good responders. This could reduce unnecessary surgeries, guide personalized treatment, and motivate broader validation of advanced diffusion models in clinical oncology.
  Figure 466-02-008.  Diagnostic Value of Magnetization Transfer and Diffusion MRI for Differentiating Fibroadenoma and Invasive Breast Carcinoma
Lingqiao Yang, Xueying Zhao, Yingqi Li, Jiuping Liang
Shenzhen Bao'an Distrct Songgang People's Hospital, Shenzhen, China
Impact:  Integrating MT and ADC enhances breast MRI specificity, enabling precise, early distinction of benign and malignant lesions. This quantitative approach supports personalized management, reduces unnecessary interventions, and translates advanced imaging into actionable clinical decision-making for improved patient outcomes.
  Figure 466-02-009.  Predicting Induction Chemotherapy Response Based on Tumor-stroma ratio Pretreatment Synthetic MRI in Nasopharyngeal Carcinoma
Huanhuan Ren, Yulin Wang, Qian Xu, Daihong Liu, Xinyu Chen, Junhao Huang, 菁 张, Hong Yu, Yong Tan, Lisha Nie, Jiuquan Zhang
Chongqing, chongqing, China
Impact: Using the nomogram were useful in selecting candidate patients for induction chemotherapy based on pretreatment synthetic MRI, which has potential clinical value in guiding clinical decision-making and improving survival.
  Figure 466-02-010.  Accurate Quantification of Adipose Tissue at Both Morphological and Microscopic Levels Using DIXON Sequence
NA ZHU, Shaolong Chen, Meimei Zhang, Xiaodong Zhang
The Third Affiliated Hospital Southern Medical University, Guangzhou, China
Impact: The T1-weighted two-point VIBE Dixon sequence enables simultaneous quantification of adipose tissue at both morphological and microscopic levels precisely, providing a novel and comprehensive approach for fat segmentation and quantification.
  Figure 466-02-011.  Repeatability of Renal Magnetic Resonance Elastography Across Frequencies and Vendors
Caixin Qiu, Hao Wu, Kevin Glaser, Peng Xu, Jiahui Li, Yuan Le, Safoura Sadegh Pour Aji Bishe, Douglas Simonetto, Sudhakar Venkatesh, Armando Manduca, Vijay Shah, Richard Ehman, Meng Yin
Mayo Clinic, Rochester, United States of America
Impact: Renal MRE stiffness demonstrates high between-day repeatability across frequencies and vendors, with RC ≤ 15% and ICC ≥0.8. These findings establish practical thresholds for distinguishing true biological change from measurement variability and support longitudinal and multicenter applications of renal MRE.
  Figure 466-02-012.  Quantitative Evaluation of Prostate Cancer Using Hybrid Multidimensional MRI: Mapping Tissue Microstructure
Durgesh Dwivedi, Aritrick Chatterjee, Sanjoy Sureka, Gregory Karczmar, Supriya Devi, Siddhant Gupta, Abhavya Raja, Siddharth Singh, Arpan Yadav, BV Rathish Kumar, Sudhir Pathak, Ranjeet Jha, Nitin Dikshit, Apul Goel, Manoj Kumar, Anit Parihar
King George's Medical University, Lucknow, India
Impact: Hybrid multidimensional MRI (HM-MRI) enables precise, non-invasive prostate tissue microstructure quantification, objectively differentiating various grades of prostate cancer. It reduces contrast use, surpasses diagnostic confidence of multiparametric MRI, and overcomes PI-RADS variability/subjectivity for reliable, personalized prostate cancer management.
  Figure 466-02-013.  Evaluation of hydration effect on water T1 across liver segments using accelerated water T1 mapping
Elizabeth Huaroc Moquillaza, Lisa Steinhelfer, Waldemar Sapototzki, Robert Walter, Kilian Weiss, Mariya Doneva, Dimitrios Karampinos, Rickmer Braren
Technical University of Munich, Munich, Germany
Impact: This study demonstrates that wT1 is influenced by both hydration status and spatial heterogeneity across the liver. These findings underline the need to control for physiological and regional factors to ensure accurate and reproducible liver wT1 quantification.
  Figure 466-02-014.  Reducing Fat–Water Swaps and Field Map Artifacts via Echo Dependent Phase Reconstruction for Liver QSM
Asli Alpman, Hongjiang Wei, Chunlei Liu
University of California, Berkeley, United States of America
Impact: Modeling non-chemical shift phase as a single frequency shift in conventional fat–water separation can cause swaps and inaccurate field maps. Incorporating echo-dependent residual phase into the signal model improves fat separation and yields more reliable tissue phase for liver QSM.
  Figure 466-02-015.  Validation and Exploratory Analysis of an Automated MRI Body Composition Analysis Tool in a WB-MRI Cancer Screening Cohort
Cornelius Jacob, Robert Grimm, Marco Stella, Majd Helo, Paul Summers, Giuseppe Petralia
Research & Clinical Translation, Magnetic Resonance, Siemens Healthineers AG, Erlangen, Germany
Impact: This study validates and applies a fully automated framework for quantitative MRI body composition analysis, enabling opportunistic extraction of metabolic, oncologic, and physiological biomarkers and supporting exploratory assessment of population-based body-composition trends in asymptomatic individuals across clinical and research settings.

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