Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026

Digital Poster

Image Classification for Brain Cancer

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Image Classification for Brain Cancer
Digital Poster
Analysis Methods
Wednesday, 13 May 2026
Digital Posters Row D
13:40 - 14:35
Session Number: 563-03
No CME/CE Credit
This session will highlight recent advances in brain cancer imaging and classification, with a focus on quantitative and AI-based approaches. Contributions will span methodological developments and clinical applications, reflecting current challenges and opportunities in the field.
Skill Level: Intermediate

  Figure 563-03-001.  Physics-Informed Multi-Parametric Machine Learning Model to Differentiate Glioblastomas and Brain Metastases
Seyyed Ali Hosseini, Archith Rajan, Nesrine Rahmouni, Arthur C. Macedo, Tevy Chan, Gleb Bezgin, Steven Brem, Stephen Bagley, Mohamad Nazem-Zadeh, Pedro Rosa‐Neto, Suyash Mohan, Sanjeev Chawla
McGill University, Montreal, Canada
Impact: By incorporating physics laws into multiparametric MRI, machine learning based models can better capture tumor biology, leading to development of more transparent and reliable clinical decision tools.
  Figure 563-03-002.  A Comparison of Radio-Pathomic, Diffusion, and Perfusion Imaging Features for Identifying Pseudoprogression in Gliomas
Samuel Bobholz, Aleksandra Winiarz, Benjamin Chao, Hope Reecher, Daniel Kim, Allison Lowman, Biprojit Nath, Savannah Duenweg, Adam Lahrache, Mrina Mtenga, Fitzgerald Kyereme, Michael Barrett, Jennifer Connelly, Elaine Tanhehco, Max Krucoff, Mohit Agarwal, Jamie Jacobsohn, Rupen Desai, Jennifer Tuscher, Peter LaViolette
Medical College of Wisconsin, Wauwatosa, United States of America
Impact: Radio-pathomic maps outperform current advanced imaging techniques in distinguishing true progression from pseudoprogression in post-treatment glioma patients in the UCSF-PTGBM dataset, potentially offering clinicians a more accurate, non-invasive tool for treatment decisions without requiring additional contrast agents or scan time.
  Figure 563-03-003.  Microstructure characterisation of brain tumours by VERDICT MRI: a benchmark of deep learning methods
Matteo Figini, Zheng Yu, Marco Palombo, Michele Bailo, Antonella Castellano, Daniel Alexander, Eleftheria Panagiotaki
University College London, London, United Kingdom
Impact: This benchmark establishes performance baselines and a reproducible evaluation framework for Deep-Learning-based VERDICT, laying groundwork for further work for the clinical translation of fast non-invasive brain tumour microstructure imaging.
  Figure 563-03-004.  Metabolic, Perfusion, and Diffusion Imaging Enhance Diagnosis and Prognosis of H3K27-Altered Diffuse Midline Gliomas
QIU JUN, Jinyuan Weng, Wei Wei
The First Affiliated Hospital of USTC, Hefei, China
Impact: This study demonstrates that integrating APTw, ASL, and DKI metrics significantly improves diagnosis and prognosis for H3K27-altered DMGs, enabling better clinical decision-making and providing a non-invasive imaging biomarker for patient stratification.
  Figure 563-03-005.  Optimized Time-Dependent Diffusion MRI for Preoperative Molecular Subtyping of Adult Diffuse Gliomas
Xin Ge, Yuhui Xiong, Jing Zhang, Wen Wang
Tangdu Hospital, Fourth Military Medical University, Xi'an, China
Impact: Optimized TDD-MRI with Bayesian IMPULSED produces reproducible microstructural maps and accurate preoperative IDH/1p/19q subtyping, informing surgical strategy and trial-ready therapy selection, while enabling voxelwise prognostication, treatment monitoring, and multicenter standardization of diffusion-time biomarkers.
  Figure 563-03-006.  Impact of incorporating T2 relaxation in the VERDICT model for brain tumor microstructure imaging
Lukas Lundholm, Oscar Jalnefjord, Mikael Montelius, Mats Laesser, Thomas Bontell, Alba Corell, Asgeir Jakola, Isabella Björkman-Burtscher, Maria Ljungberg
University of Gothenburg, Gothenburg, Sweden
Impact: Including compartment-specific T2 relaxation in the VERDICT model substantially alters parameter estimates in brain tumors, indicating that neglecting T2 differences may bias results and that accounting for this effect may be critical for accurate estimation of VERDICT-derived parameters.
  Figure 563-03-007.  Characterisation of brain tumour type using multi-parametric information from GE-SE EPIK
Fabian Küppers, Keith George Ciantar, Seong Dae Yun, Gabriele Stoffels, Christian Filß, Norbert Galldiks, Felix Mottaghy, M. Eline Kooi, Karl-Josef Langen, Philipp Lohmann, N. Jon Shah
Forschungszentrum Juelich, Juelich, Germany
Impact: GE-SE EPIK-derived mean OEF and R2’ change with respect to different FET TBR thresholds used for tumour VOI segmentation, while R2’ show potential to differentiate astrocytoma. Parameter combinations improve the significance of tumour type differences compared to single parameters.
  Figure 563-03-008.  Accurate and Robust Brain Tumor Classification with Vision Transformer Models
Dr. Abdullah Asiri
Najran University, Najran, Saudi Arabia
Impact: This study advances clinical neuroimaging by demonstrating that Swin Transformer models significantly enhance brain tumor classification accuracy.The findings empower radiologists with reliable diagnostic support tools,encourage broader application of transformer-based AI in medical imaging, and inspire future research on cross-modality generalization.
  Figure 563-03-009.  Comparative Evaluation of Brain Tissue Stiffness in Pituitary Adenoma and Healthy Volunteers Using MR Elastography
Shivani Tripathi, Priyanka Bhat, Ashish Suri, Ajay Garg, Yogesh k Mariappan, Sandeep Ganji, Poonam Choudhary, S Senthil Kumaran
All India Institute of Medical Sciences, New Delhi, India
Impact: Brain MR Elastography non-invasively quantifies pituitary adenoma stiffness, aiding preoperative planning and potentially improving surgical precision and patient outcomes.
  Figure 563-03-010.  MRI-Driven Finite Element Analysis for Patient-Specific Glioma Biomechanics
Enamul Bhuiyan, Md Mazder Rahman, Xiaohong Joe Zhou
University of Illinois Chicago, Chicago, United States of America
Impact: This physics-informed pipeline enables the estimation of interpretable biomechanical properties, offering a scalable, noninvasive, and clinically translatable tool for glioma assessment with further validations.
  Figure 563-03-011.  Hybrid 3D U-Net and Hyperdimensional Architecture for Efficient Brain Tumor Analysis
Muhammad Saad Ullah, Iqra Akhtar
COMSATS University Islamabad, Islamabad, Pakistan
Impact: Through this novel coil technology, a fundamental hardware technology provides us higher SNR and data acquisition acceleration across MRI applications. This empowers the clinical diagnostics with improved resolution and speed, and offers researchers to ground-break new biomedical studies.
  Figure 563-03-012.  Sodium MRI and MR Elastography as Quantitative Biomarkers in Pediatric Brain Tumors: A Translational Approach
L Tyler Williams, Katrina Milbocker, Sabrina Vander Wiele, Grace McIlvain, Em Triolo, N Ece Yilmaz, Suraj Serai, Raisa Amiruddin, Peter Madsen, Lina Chihoub, Curtis Johnson, Timothy Roberts, Aashim Bhatia
Children's Hospital of Philadelphia, Philadelphia, United States of America
Impact: This translational pilot study helps establish the value of sodium (23Na) MRI and MR Elastography (MRE) as imaging biomarkers in pediatric brain tumors which may improve neurosurgical planning and our ability to detect treatment resistant tumor regions and tumor progression.
  Figure 563-03-013.  NOE MRI for Improved Brain Tumor Infiltration
Blake Benyard, Narayan Datt Soni, Anshuman Swain, Nishi Srivastava, Sunil Khokhar, Nadir Yehya, Yi Fan, Dushyant Kumar, RAVI PRAKASH REDDY NANGA, Michael Frenneaux, Mohammad Haris, Ravinder Reddy
University of Pennsylvania, Philadelphia, United States of America
Impact: This method could enhance the assessment of tumor boundaries for surgical and radiation treatment planning.
  Figure 563-03-014.  Imaging Microstructural Environment in Patients with Brain Metastasis and Meningioma: Preliminary Findings from SANDI
Sang-Young Kim, Eunju Kim, Jinwoo Hwang, Eung Yeop Kim, Sung Tae Kim, Beomseok Sohn
Philips Korea, Seoul, Korea, Republic of
Impact: Diffusion MRI with SANDI model would offer a non-invasive way to distinguish brain tumor phenotypes by probing cell body and neurite features, which may provide microstructural biomarkers.

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