Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026

Digital Poster

Classification and Analysis in the Brain

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Classification and Analysis in the Brain
Digital Poster
Analysis Methods
Monday, 11 May 2026
Digital Posters Row D
16:10 - 17:05
Session Number: 363-05
No CME/CE Credit
This session focusses on image analysis and tools using data processing and AI methods to classify the brain.

  Figure 363-05-001.  Neuroimaging-Based Analysis: Structural Brain Abnormalities and Diagnostic Classification of Ménière's Disease
Wenliang Fan
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Impact: MD patients showed substantial alteration in gray matter volume and surface indexes across frontal and cingulate gyri.our classification model, incorporating a comprehensive array of neuroimaging features, achieved an impressive accuracy of 84% in distinguishing MD patients from HC.
  Figure 363-05-002.  Comparative Analysis of Radiologist, Radiomics, and Multidimensional Deep Learning for Preoperative Molecular Classification
Xin Ge, Yuhui Xiong, Jing Zhang, Wen Wang
Tangdu Hospital, Fourth Military Medical University, Xi'an, China
Impact: Standardized quantitative MRI and head-to-head benchmarking identify a deployable 2.5D deep-learning ensemble that improves IDH/1p/19q classification and independent survival stratification, informing preoperative decisions and enabling multicenter, vendor-agnostic trials, prospective utility studies, and AI-assisted treatment selection in neuro-oncology.
  Figure 363-05-003.  Automated Motion Artifact Check for MRI (AutoMAC-MRI): Explainable severity grading of motion artifacts in MR images
Antony Jerald, Dattesh Dayanand Shanbhag, SUDHANYA Chatterjee
GE HealthCare, Bengaluru, India
Impact: Automated, explainable MRI motion artifact grading accelerates workflows, reduces patient recalls, and improves diagnostic confidence. It empowers clinicians with actionable insights, enhances patient comfort, and opens new research directions in explainable motion detection and severity grading.
  Figure 363-05-004.  Classification of tumor treatment response from multi-time point multisequence MRI scans
Ewunate Kassaw, Satyajit Maurya, Amit Mehndiratta, Anup Singh
Indian Institute of Technology, Delhi, India
Impact: This study presents an objective and automated approach for evaluating the progress of brain tumor treatment response from multiparametric longitudinal MR scans. This can contribute to the non-invasive and timely diagnosis and treatment of patients.
  Figure 363-05-005.  Premature brain volume reduction and its dynamics in the early course of multiple sclerosis
Hagen Kitzler, Thomas Pollinger, Caroline Koehler, Tjalf Ziemssen, Paul Kuntke
Technical University of Dresden, Dresden, Germany
Impact: This work provides in vivo evidence of significant differences in age-corrected brain volumes between patients in the early MS compared to healthy controls. Our approach of population-based atrophy categorization and dynamics provides early identification of risk groups with accelerated neurodegeneration.
  Figure 363-05-006.  SynthScore: predicting reference-based motion artifact scores without a reference image
Tamsin Edwards Lambourne, Yuh-Shin Chang, Brooks Applewhite, Malte Hoffmann, Robert Frost
Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Charlestown, United States of America
Impact: We present a deep-learning model where our predicted motion artifact scores have a similar correlation level with radiologist assessment as reference-based metrics, demonstrating applicability for settings where reference images are unavailable, and expert assessment is impractical.
  Figure 363-05-007.  Impact of MRI Acceleration using Compressed SENSE on Brain Cortical Thickness Measurements
Laura Leukert, Fabian Bongratz, Benita Schmitz-Koep, Michael Dieckmeyer, Jan Kirschke, Dennis M Hedderich
TUM School of Medicine and Health, Munich, Germany
Impact: Differences in MRI acceleration, image quality and software implementation measurably influence brain cortical thickness estimates. These factors must be considered while interpreting morphometric studies to avoid misclassification of neurodegenerative change and to ensure reliable clinical decision-making in longitudinal patient care.
  Figure 363-05-008.  Deep Learning with MRI and Clinical Data for Differentiation of Radiation Injury from Tumor Recurrence in Brain Metastases
Yuhan Liang, Zelong Chen, Menglin Ge, Yulin Wang
Chinese PLA General Hospital, Beijing, China
Impact: This deep learning tool noninvasively distinguishes radiation injury from tumor recurrence in brain metastases with over 91% accuracy, potentially reducing unnecessary biopsies and optimizing post-radiotherapy management.
  Figure 363-05-009.  Highly Accelerated Brain MRI Matches Routine Scans for AI Image Analysis Task Performance
Moona Mazher, Miguel Rosa-Grilo, Haroon Chughtai, David Thomas, Millie Beament, Frederik Barkhof, Catherine J. Mummery, Nick C. Fox, Geoff Parker, Daniel Alexander
University College London, London, United Kingdom
Impact: Ultra-fast MRI scans analysed with a foundation model achieve comparable performance to routine scans, supporting their clinical adoption. This enables rapid, reliable neuroimaging, improving patient throughput, accessibility, and scalable workflows without sacrificing diagnostic accuracy.
  Figure 363-05-010.  Deep learning MRI model for transcription factor-based classification of pituitary neuroendocrine tumor subtypes
Elizabeth Ndimulunde, Bing-Fong Lin, Dao-Chen Lin, Chia-Feng Lu
National Yang Ming Chiao Tung University, Taipei, Taiwan
Impact: This study demonstrates the potential of MRI-based deep learning for comprehensive, non-invasive lineage classification for pituitary neuroendocrine tumors, reducing dependence on postoperative immunohistochemistry and enabling improved preoperative diagnostic accuracy and personalized treatment planning.
  Figure 363-05-011.  Improving ME-ICA for task fMRI in susceptibility-affected brain regions at 7 Tesla
Toshiki Okumura, Ikuhiro Kida
Center for Information and Neural Networks, National Institute of Information and Communications Technology, Osaka, Japan
Impact: Majority vote increased ME-ICA classification robustness and improved fMRI analysis (GLM and decoding analyses), particularly when including brain regions affected by susceptibility artifacts.
  Figure 363-05-012.  Exploring Brain Iron Deposition in Thalassemia Using Sub-voxel QSM and Machine Learning Models for Accurate Diagnosis
Mingrui Yang, Peng Peng, Huang Yugui, Chunxia Zhu, Jiatong Liang, Guowei Chen, Kong Rong, Cheng Tang, Hui Zhang
The First Affiliated Hospital of Guangxi Medical University,, Nanning, China
Impact: This study applies the innovative sub-voxel QSM (Chi-separation) technique with machine learning and SHAP analysis to accurately diagnose brain iron deposition in thalassemia, providing new insights for early diagnosis and monitoring.
  Figure 363-05-013.  Geometric properties of caudate and putamen mark the progression of Huntington’s disease
Dorian Pustina, Haikel Bogale, Sandhitsu Das, Brian Avants, Swati Sathe, Cristina Sampaio, Andrew Wood
CHDI Management, United States of America
Impact: The striatum’s geometry holds untapped biomarker potential. The striatum does not simply shrink, it changes shape. Even using imperfect segmentations, geometric descriptors reveal disease-related signatures that complement volumetric loss.
  Figure 363-05-014.  Do Perivascular Space Abnormalities in the Brain Differ Among Various Disease States?
Thais Bezerra, Zhibin Chen, Lucas Scárdua Silva, Brunno Machado de Campos, Gabriel de Deus Vieira, Thiago Rezende, Alfredo Damasceno, Simone Appenzeller, Marcio Balthazar, Marcondes Cavalcante França Junior, Leonilda Santos, Felipe Von Glehn Silva, Patrick Kwan, Terence O'Brien, Fernando Cendes, Meng Law, Clarissa Yasuda, Ben Sinclair
University of Campinas, Campinas, Brazil
Impact: Here we provide evidence that there are distinct distributions of PVS abnormalities between different diseases, indicating that PVS may be more than just a general marker of brain health, but are affected differently in different diseases.
  Figure 363-05-015.  Random matrix theory denoising for preclinical diffusion MRI
Ricardo Coronado-Leija, Yoko Bekku, Jiangyang Zhang, James Salzer, Els Fieremans, Dmitry Novikov
Center for Advanced Imaging Innovation and Research (CAI²R), New York University Grossman School of Medicine, New York, United States of America
Impact: Preclinical scanners achieve very strong diffusion weightings, but these are typically not used due to low signal-to-noise ratio and noise floor constraints. Here, we demonstrate how random matrix theory denoising before image reconstruction improves preclinical high $b$-value diffusion MRI.
  Figure 363-05-016.  T2-Weighted Contrasts and Manual Editing Significantly Affect FreeSurfer Cortical Morphometry and Clinical Associations
Haley Wiskoski, Summan Zahra, Juan Arias, Scott French, Kevin Johnson, Simeon Smith, Caleb Boehler, Raza Mushtaq, Maria Altbach, Gene Alexander, Theodore Trouard, Craig Weinkauf
University of Arizona, Tucson, United States of America
Impact: This study demonstrates that adding T2-weighted images to FreeSurfer systematically alters cortical morphometry and weakens biological associations. Establishing that T1-only pipelines, with manual editing, yield more reliable results supports methodological standardization and enhances reproducibility across neuroimaging and Alzheimer’s disease research.

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