Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026

Digital Poster

Quantitative MRI Software: Tools and Applications

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Quantitative MRI Software: Tools and Applications
Digital Poster
Analysis Methods
Thursday, 14 May 2026
Digital Posters Row I
13:40 - 14:35
Session Number: 668-03
No CME/CE Credit
Software tools for quantitative MR imaging across organs

  Figure 668-03-001.  Open-Source Multi-Echo (TE) MRI Tool for Arterial Spin Labelling Imaging Protocols: Advanced Features in ASLtoolkit
Antonio Carlos Senra Filho, Andre Paschoal
University of Campinas, Campinas, Brazil
Impact: Computational complexity hinders advanced ASL adoption. Our open-source, cross-platform ASLtoolkit simplifies multi-echo analysis (via CLI and 3D Slicer), enabling reproducible research on perfusion and BBB permeability, accelerating the study of neurovascular diseases.
  Figure 668-03-002.  microTorch: a software framework for fast and flexible diffusion MRI model fitting
Snigdha Sen, Rajib Ahmed, Gerrit Arends, Álvaro Planchuelo-Gómez, Xiaoxiang Chen, Marta Masramon, Christopher Parker, Marco Palombo, Chantal Tax, Eleftheria Panagiotaki, Paddy Slator
UCL, London, United Kingdom
Impact: Self-supervised model fitting is a promising technique in diffusion MRI. However, implementing different microstructure models and architectures remains challenging without a unified code base. Our microTorch framework simplifies self-supervised fitting, facilitating code sharing and reproducibility in diffusion MRI research.
  Figure 668-03-003.  VASAL: A Vascular Substrate Algorithm to Generate Microvascular Network Phantoms
Elizabeth Powell, Geoff Parker, Marco Palombo
University College London, London, United Kingdom
Impact: VASAL enables in-silico blood flow simulations in realistic microvascular networks, enabling optimisation of dMRI sequences for sensitivity to specific microvascular features, validation of biophysical models, interpretation of subtle signal changes, and study of pathological microvascular alterations.
  Figure 668-03-004.  Rapid Physics-Consistent QTI Model Fitting using a Hierarchical Encoder-Decoder Network
Wenwen Sun, Mahsa Rajabi, Mathews Jacob, Merry Mani
University of Virginia, Charlottesville, United States of America
Impact: By delivering rapid, physics-consistent QTI parameters from tensor-valued diffusion signals, our method enables whole-brain microstructure mapping in seconds, improves robustness for accelerated protocols, and broadens clinical adoption for disease characterization and large-scale cohort studies.
  Figure 668-03-005.  Accurate Estimation of Intravoxel Incoherent Motion Parameters Based on Implicit Neural Representation
Yunxiang Li, Yen-peng Liao, Yan Dai, Jie Deng, You Zhang
University of Texas Southwestern Medical Center, Dallas, United States of America
Impact: By combining INR's continuous function modeling capability with spatial-aware feature design, IVIM-INR overcomes the inherent limitations of traditional methods under noisy conditions, providing a more reliable tool for clinical IVIM quantitative analysis.
  Figure 668-03-006.  Enabling Highly Accelerated Multi-shot IVIM-DWI with a DL Framework: Joint Image Reconstruction and Biomarker Estimation
Chenglang Yuan, Shihui Chen, Liyuan Liang, Xiaorui Xu, HAILIN XIONG, Yi Li, Tianbaige Liu, QITING WU, Wing Yat Cheung, Sai Kam Hui, Qi DOU, Hing-Chiu Chang
The Chinese University of Hong Kong, Hong Kong, China
Impact: The proposed data-sharing-guided framework enables the joint reconstruction of DW-images and the estimation of IVIM-biomarkers from highly accelerated 4-shot IVIM-DWI data, potentially improving quantitative IVIM-DWI assessment in cerebrovascular and neurological diseases.
  Figure 668-03-007.  Protocol generalisation for brain tissue microstructure estimation with geometric deep learning: a hypernetwork approach
Andrea Brigliadori, Gary Zhang, Leevi Kerkelä
University College London, London, United Kingdom
Impact: The proposed work provides clinicians with a single machine learning model to obtain parametric maps regardless of b-value pair, b-vector directions, or fibre-direction distribution. This reduces retraining needs and improves clinical viability of microstructure estimation.
  Figure 668-03-008.  Kidneys are on FIRE
Luis Sanmiguel, Pieter de Visschere, Pim Pullens
Ghent University Hospital, Gent, Belgium
Impact: By automating renal T1 mapping and delivering instant inline post-processing results, which are also stored in Picture Archiving and Communication System (PACS), this framework removes key workflow barriers, with the target to accelerate the clinical adoption of renal MRI.
  Figure 668-03-009.  Non-Gaussian Noise in AMARES Quantification Systematically Biases Dynamic MRS Kinetic Parameters
Christoffer Laustsen, Jack Miller
Aarhus University, Aarhus, Denmark
Impact: Spectral quantification algorithms produce non-Gaussian noise that systematically biases kinetic parameters in dynamic MRS. This affects multicentre trial comparability and diagnostic thresholds for both hyperpolarized 13C and 2H DMI, requiring noise characterization and reporting of spectral SNR.
  Figure 668-03-010.  Finding variance line artifacts in FMRI data using AFNI
Paul Taylor, Daniel Glen, Justin Rajendra, Richard Reynolds
National Institute of Mental Health, Bethesda, United States of America
Impact: Detecting and eliminating artifacts is important for researchers and clinicians. We describe a newly observed spatiotemporal artifact present in many FMRI collections, plus a tool to detect it. This improves quality control, artifact reduction, and reproducibility in neuroimaging.
  Figure 668-03-011.  An open standard for storing and transmitting an RF coil’s ID and detailed operating parameters to the scanner.
Umberto Zanovello, Nicola De Zanche
Istituto Nazionale di Ricerca Metrologica, Turin, Italy
Impact: The proposed standard data format and transmission protocol identifies an RF coil's capabilities and operating parameters to the scanner. The standard meets the needs of the growing open-source MR community and makes the use of a local ID file unnecessary.
  Figure 668-03-012.  An automated pipeline to verify electrode positions in concurrent tDCS-MRI studies
Sina Straub, Raphaela Schöpfer, Sarah Godehardt, Florian Wüthrich, Jessica Peter
University of Bern, Bern, Switzerland
Impact: Our newly developed automated pipeline extracts electrode coordinates from MRI data, enabling large-scale verification of placement accuracy. With our pipeline, deviations from intended electrode positions can be linked to stimulation effects. In the future, this may facilitate reproducible tDCS research.
  Figure 668-03-013.  Reproducibility of intravoxel incoherent motion imaging: impact of the fitting algorithm
Ben Neijndorff, Daan Kuppens, Ivan Rashid, Oscar Jalnefjord, Eric Peterson, Petra van Houdt, Oliver Gurney-Champion
the Netherlands Cancer Institute, Amsterdam, Netherlands
Impact: By comparing IVIM fitting algorithms from the OSIPI IVIM code repository the impact of algorithm design choices on the reproducibility of IVIM parameters was assessed. Segmented nonlinear least squares algorithms showed the most reproducible results in simulated and in-vivo data.
  Figure 668-03-014.  Streamlining Multi-Site Neuroimaging Workflows: A Unified Interface for Data Harmonization, QC, and Analysis
Hajer Karoui, Petter Clemensson, Aksel Leknes, Petra Kis-Herczegh, Ethan Nott, Sean Deoni, Steven Williams, Niall Bourke
Centre for Neuroimaging Sciences, King's College London, London, United Kingdom
Impact: This tool streamlines multi-site neuroimaging workflows by uploading, harmonizing, cleaning, and QCing data from diverse LMIC studies. It enables efficient derivative retrieval, visualization, and batch analysis, improving data quality, reproducibility, and accessibility for modeling and collaboration across sites.
  Figure 668-03-015.  Shape metric guided voxel localization for magnetic resonance spectroscopy with VoxLoc
Keith Werling, Sairam Geethanath, Etoku Oiye, Lazar Fleysher, Keren Bachi
Icahn School of Medicine at Mount Sinai, New York, United States of America
Impact: An open-source, vendor-independent automated voxel localization tool, VoxLoc, in combination with existing fast and robust atlas-based image processing pipelines demonstrates plausible broad-use in real-time Magnetic Resonance Spectroscopy (MRS) study applications of brain pathology and psychiatric disorders.

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