Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026

Traditional Poster

Decoding Stroke with Imaging and AI: New Frontiers in Cerebrovascular Research

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Decoding Stroke with Imaging and AI: New Frontiers in Cerebrovascular Research
Traditional Poster
Neuro A
Tuesday, 12 May 2026
Traditional Posters | Exhibition Hall
08:20 - 09:15
Session Number: 470-02
No CME/CE Credit
This traditional poster session focuses on innovative imaging and computational approaches to improve the detection, characterization, and prognosis of stroke and cerebrovascular injury. Presentations span advanced MRI techniques (e.g., diffusion models, APTw imaging, vascular fingerprinting, susceptibility imaging), physiological and biochemical markers of ischemia, and machine learning models for outcome prediction. Several studies also introduce synthetic data generation and mechanistic modeling to support robust algorithm development. Together, these posters highlight how quantitative imaging and AI-driven methods can deepen understanding of stroke pathophysiology and support more precise clinical decision-making.

  Figure 470-02-079.  Predicting Longitudinal Language Deficits with Connectome‑Thresholded Graph Neural Networks on Brain Connectivity
Qiao Deng, Yuming Zhong, Sai Kam Hui
The Chinese University of Hong Kong, Shatin, Hong Kong
Impact: CT‑GNN enables earlier, patient-specific prognostication of post‑stroke language trajectories.
  Figure 470-02-080.  Deep Learning and Brain Parcellation–Based Machine Learning Model for Prognosis after Acute Ischemic Stroke
Tung-Yang Lee, Chun-Jung Juan, Shao-Chieh Lin, Chia-Ching Chang, Cheng-Hsuan Juan, Cheng-En Juan, Ya-Hui Li, Yi-Jui Liu
Feng Chia University, Taichung, Taiwan
Impact: Integrating deep learning–based lesion segmentation, brain parcellation, and machine-learning classification with demographic information enables objective and accurate 3-month outcome prediction after acute ischemic stroke, enhancing precision medicine and supporting personalized, evidence-based decision-making in stroke management.
  Figure 470-02-081.  Clinical Value of Rapid Amide Proton Transfer-weighted Imaging in Detecting Ischemic Penumbra in Acute Cerebral Infarction
Jimei Tang, Zhiqiang Chang, Zhiwei Shen
Xing’an League People’s Hospital, Inner Mongolia, China
Impact: Currently, the use of APTw technology to assess acute ischemic stroke is predominantly concentrated in animal studies, with clinical research focusing on patients with a disease duration of less than 24 hours being rather rare.
  Figure 470-02-082.  Extended MR Vascular Fingerprinting for the study of brain lesions: implementation and tests in a stroke model
Maitê Marçal, Thomas Coudert, Aurélien Delphin, Daniil Kirdyashkin, Antoine Barrier, Emmanuel BARBIER, Benjamin Lemasson, Thomas Christen
Univ. Grenoble Alpes, INSERM, U1216, Grenoble Institute Neurosciences, GIN, Grenoble, France
Impact: MR-vascular Fingerprinting using realistic geometries and advanced simulations models allows the simultaneous evaluation of multiple microvascular properties. The proposed extended framework better characterizes brain microvasculature, and could potentially improve stroke management.
  Figure 470-02-083.  Evaluation of pH Changes in Brain Infarction with MTRasym and MRAPTR in APTw MRI and its Influencing Factors
Huan Li, Tanoj Bahadur Singh, Ting Liu, Tianhao Wang, Danni Huang, Yin Wu, Hao dong Qin, Jianzhong Yin
Haikou People's Hospital, haikou, China
Impact: This research tackles the clinical challenge of standardizing APTw-MRI in ischemic stroke. The findings confirm the higher diagnostic performance of MRAPTR and advance the clinical translation of APTw-MRI by defining its limitations and reliability.
  Figure 470-02-084.  Synthetic Stroke Lesion Generation Based on Mechanistic Principles and Label to Image Methodology
Aksel Leknes, Ayo Zahra, Ketil Oppedal, Kathinka Kurz, Martin Kurz, Thomas Lindner, Soffien Ajmi, Muriel Bruchhage
University of Stavanger, STAVANGER, Norway
Impact: Developing synthetic stroke images can be a basis for robust stroke segmentation models across modalities and contrasts. Additionally, the mechanistic approach of lesion generation can serve as a basis for descriptive and predictive stroke analysis tools.
  Figure 470-02-085.  Alterations in Brain Iron in the Basal Ganglia of Acute Ischemic Stroke Patients: A Susceptibility Source Separation Imaging
Jie Yang, Shenghai Zhou, Hao Feng, Meining Chen, Wei Sheng, Hui Zhang, Jianquan Zhong
First People's Hospital of Zigong City, Zigong, China
Impact: Susceptibility source separation technology may provide a new advantageous tool for detecting abnormal brain iron deposition in the basal ganglia of AIS patients.
  Figure 470-02-086.  White matter hyperintensity burden as a predictor of white matter damage
Hyeong-Geol Shin, Sarvin Sasannia, Mykola Matsyuk, Shimeng Wang, Jinwei Zhang, Xu Li, Filip Szczepankiewicz, Jerry Prince, Richard Leigh, Linda Knutsson, Peter van Zijl, Paul Nyquist
Johns Hopkins University, Baltimore, United States of America
Impact: Cross-sectional WMH burden better captures ongoing white matter degeneration (measured by diffusion MRI), outperforming BBB permeability indicators and WMH burden progression history, highlighting the potential of a simple volumetric parameter as a clinically relevant biomarker of small vessel disease–related injury.
  Figure 470-02-087.  Automatic Quantification of Ischemic Core, Penumbra, and Perfusion–Diffusion Mismatch using Perfusion and Diffusion MRI
Anup Singh, Ankit Kandpal, Rakesh Kumar Gupta
Indian Institute of Technology, Delhi, India
Impact: This study presents an endogenous contrast-based, rapid, and fully automated deep-learning framework that segments ischemic core and penumbra and quantifies perfusion–diffusion mismatch from multiparametric MRI, enabling accurate and reproducible stroke assessment to support real-time clinical decision-making.

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