Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026
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464-04-001.
Clinical translation of the ROMER-EPTI technique for diffusion-MRI based detection of epileptogenic lesions: A pilot study
Impact: This study will demonstrate high-resolution microstructure diffusion MRI in focal epilepsy and clinical translation of advanced acquisition technologies, with potential to improve lesion detection, guide surgical planning, and advance our understanding of disease-related tissue alterations.
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464-04-002.
Correlation between diffusion MRI-based corticospinal tract microstructure and motor function outcomes in a rat stroke model
Impact: Diffusion magnetic resonance imaging (dMRI)-based markers of corticospinal tract (CST) microstructure that correlate with corticospinal excitability and motor function after stroke may aid in patient outcome prediction.
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464-04-003.
Does Denoising Reduce Cross-Vendor Variability in Diffusion MRI? A Travelling Heads Evaluation
Impact: Harmonising
MRI data is vital to ensure imaging-derived research outcomes are reproducible.
Using travelling heads, we will explore the interaction between susceptibility artefacts and denoising scan repeats.Furthermore, we will evaluate denoising’s ability to reduce cross-vendor variance in diffusion MRI.
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464-04-004.
Developing and Validating a Novel DTI-Based Analysis Framework for Investigating Cortical Perivascular Transport in the Brain
Impact: By measuring diffusivity aligned with perivascular pathways, the proposed framework aims to establish a novel sensitive marker of glymphatic function in the cerebral cortex, supporting earlier detection and progress assessment of glymphatic impairments associated with neurodegenerative disorders.
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464-04-005.
Cross-Validating SANDI and IMPULSED Cell Diameter Maps in Human Gray Matter Using a High-Performance Gradient 3.0T MRI System
Impact: Establishing
a concordance between q-space-based (SANDI) and t-space-based (IMPULSED) models would validate their joint utility and
pave the way for harmonized microstructural biomarkers, enhancing the
reliability of non-invasive studies of gray matter in development, aging, and
diseases.
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464-04-006.
Comparing in vivo Restricted Spectrum Imaging measurements at b=8000 s/mm2 and b=4000 s/mm2 in glioblastoma patients
Impact: Improved high b-value RSI could enable more accurate differentiation of tumor cellularity from edema, enhancing preoperative assessment and treatment planning for glioblastoma patients, standardizing acquisition protocols and supporting wider clinical adoption of diffusion-based tumor biomarkers for decision-making and clinical trials.
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464-04-007.
Skeletal Muscle Microstructural Alterations in Sarcopenia: Insights from Diffusion MRI
Impact: The goal of this study is to evaluate FA and MD in a cohort of 46 older adults. The current diagnostic protocols are inconsistent and often rely on functional assessment, while quantitative MRI parameters could function as early, quantitative biomarkers.
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464-04-008.
MRI in Clinical Practice: Value of Ultra-High-b-Value Reduced Field-of-View DWI in the Restaging of Rectal Cancer after TNT
Impact: Ultra-high-b-value rFOV DWI (b = 5000 s/mm²) helps resolve the diagnostic uncertainty of standard MRI in assessing cCR. By increasing diagnostic confidence, it supported the clinical decision for the patient to enter a W&W strategy.
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464-04-009.
Screening of children with family history of HHT for disease expression in brain, liver and lung by MR Imaging
Impact: Since even patients without clinical signs of HHT suffered from PAVMs and related complications, screening for possibly live-threatening AV-Malformations is necessary and MRI can evaluate disease expression of HHT with the goal of normal quality of life and life expectancy.
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