Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition • 09-14 May 2026

Digital Poster

Diffusion MRI: Registered and Clinical Abstracts

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Diffusion MRI: Registered and Clinical Abstracts
Digital Poster
Diffusion
Tuesday, 12 May 2026
Digital Posters Row E
14:35 - 15:30
Session Number: 464-04
No CME/CE Credit
This session has all dMRI abstracts that were submitted as registered abstracts or clinical abstracts

  Figure 464-04-001.  Clinical translation of the ROMER-EPTI technique for diffusion-MRI based detection of epileptogenic lesions: A pilot study
Felix Zahnert, Peter Hadar, Mingxiao Zhang, Lawrence Wald, Susie Huang, Zijing Dong, Fuyixue Wang
Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Charlestown, United States of America
Impact: This study will demonstrate high-resolution microstructure diffusion MRI in focal epilepsy and clinical translation of advanced acquisition technologies, with potential to improve lesion detection, guide surgical planning, and advance our understanding of disease-related tissue alterations.
  Figure 464-04-002.  Correlation between diffusion MRI-based corticospinal tract microstructure and motor function outcomes in a rat stroke model
Linda Reiland, Vera Wielenga, Annette Van der Toorn, Lois Chin Joe Kin, Bart Franx, Martijn Froeling, Rick Dijkhuizen
UMC Utrecht, Utrecht, Netherlands
Impact: Diffusion magnetic resonance imaging (dMRI)-based markers of corticospinal tract (CST) microstructure that correlate with corticospinal excitability and motor function after stroke may aid in patient outcome prediction.
  Figure 464-04-003.  Does Denoising Reduce Cross-Vendor Variability in Diffusion MRI? A Travelling Heads Evaluation
Francesco D'Antonio, Jose-Pedro Manzano-Patron, Olivier Mougin, Paul Morgan, Stam Sotiropoulos, Shaun Warrington
University of Nottingham, Nottingham, United Kingdom
Impact: Harmonising MRI data is vital to ensure imaging-derived research outcomes are reproducible. Using travelling heads, we will explore the interaction between susceptibility artefacts and denoising scan repeats.Furthermore, we will evaluate denoising’s ability to reduce cross-vendor variance in diffusion MRI.
  Figure 464-04-004.  Developing and Validating a Novel DTI-Based Analysis Framework for Investigating Cortical Perivascular Transport in the Brain
Juan Sebastian Bermudez, Ben Leverton, Yolanda Ohene, Ingo Schiessl, Ben Dickie
University of Manchester, Manchester, United Kingdom
Impact: By measuring diffusivity aligned with perivascular pathways, the proposed framework aims to establish a novel sensitive marker of glymphatic function in the cerebral cortex, supporting earlier detection and progress assessment of glymphatic impairments associated with neurodegenerative disorders.
  Figure 464-04-005.  Cross-Validating SANDI and IMPULSED Cell Diameter Maps in Human Gray Matter Using a High-Performance Gradient 3.0T MRI System
Ruicheng Ba, Yuhui Xiong, Bing Wu
GE HealthCare MR Research, Beijing, China
Impact: Establishing a concordance between q-space-based (SANDI) and t-space-based (IMPULSED) models would validate their joint utility and pave the way for harmonized microstructural biomarkers, enhancing the reliability of non-invasive studies of gray matter in development, aging, and diseases.
  Figure 464-04-006.  Comparing in vivo Restricted Spectrum Imaging measurements at b=8000 s/mm2 and b=4000 s/mm2 in glioblastoma patients
Philippe Dionne, Gérémy Michaud, Céline Leclerc, Éric Poulin, Maxime Descoteaux, Louis Archambault, Louis Gagnon
Université Laval, Québec, Canada
Impact: Improved high b-value RSI could enable more accurate differentiation of tumor cellularity from edema, enhancing preoperative assessment and treatment planning for glioblastoma patients, standardizing acquisition protocols and supporting wider clinical adoption of diffusion-based tumor biomarkers for decision-making and clinical trials.
  Figure 464-04-007.  Skeletal Muscle Microstructural Alterations in Sarcopenia: Insights from Diffusion MRI
Katarina Pus, Sabine Räuber, Bostjan Šimunič, Francesco Santini, Marta Maggioni
Alma Mater Europaea University, Maribor, Slovenia
Impact: The goal of this study is to evaluate FA and MD in a cohort of 46 older adults. The current diagnostic protocols are inconsistent and often rely on functional assessment, while quantitative MRI parameters could function as early, quantitative biomarkers.
  Figure 464-04-008.  MRI in Clinical Practice: Value of Ultra-High-b-Value Reduced Field-of-View DWI in the Restaging of Rectal Cancer after TNT
Guoxu Zhao, Lijuan Wan, Peng Wang, Diliang Li, Sicong Wang, Yan chaoqi, Hongmei Zhang
National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
Impact: Ultra-high-b-value rFOV DWI (b = 5000 s/mm²) helps resolve the diagnostic uncertainty of standard MRI in assessing cCR. By increasing diagnostic confidence, it supported the clinical decision for the patient to enter a W&W strategy.
  Figure 464-04-009.  Screening of children with family history of HHT for disease expression in brain, liver and lung by MR Imaging
Guenther Schneider, Diane Wagner-Jochem, Arno Buecker
Saarland University Medical Center, Homburg, Germany
Impact: Since even patients without clinical signs of HHT suffered from PAVMs and related complications, screening for possibly live-threatening AV-Malformations is necessary and MRI can evaluate disease expression of HHT with the goal of normal quality of life and life expectancy.

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