Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
304-04-004 ISMRM Abstract

Simultaneous fMRI and Optical Imaging Reveal a Broadband Cortical Neuronal Fingerprint from Theta to Infraslow Frequencies

Accepted
Wen-Ju Pan 1, Lauren C Daley1, Lisa Meyer-Baese1, Dieter Jaeger2, Shella Keilholz1
1Biomedical Engineering, Emory/Georgia Tech, Atlanta, United States of America
2Biology, Emory/Georgia Tech, Atlanta, United States of America
Presenting Author: Wen-Ju Pan

Synopsis

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References

1. Lake, E. M. et al. Simultaneous cortex-wide fluorescence Ca2+ imaging and whole-brain fMRI. Nat Methods 17, 1262–1271 (2020). PMID: 33139894 [pmid]
2. Bernard, R., Valverde Salzmann, M., Scheffler, K. & Pohmann, R. Concurrent intrinsic optical imaging and fMRI at ultra-high field using magnetic field proof optical components. NMR in Biomedicine 36, e4909 (2023). DOI: 10.1002/nbm.4909 [doi]
3. Finn, E. S. et al. Functional connectome fingerprinting: Identifying individuals using patterns of brain connectivity. Nature Neuroscience 18, 1664–1671 (2015). DOI: 10.1038/nn.4135 [doi]
4. Pan, W.-J. et al. (ISMRM 2025) Seamless integration of fMRI (EPI, ZTE) and wide-field optical imaging in mice. https://archive.ismrm.org/2025/1013.html.
5. Pan, W.-J. et al. (ISMRM 2022) Optimization of wide-field optical imaging method towards fMRI integration in mice. https://archive.ismrm.org/2022/3331.html.
6. Lu, X. et al. Widefield imaging of rapid pan-cortical voltage dynamics with an indicator evolved for one-photon microscopy. Nat Commun 14, 6423 (2023). DOI: 10.1038/s41467-023-41975-3 [doi]
7. Pan, W.-J., Anumba, N., Xu, N., Meyer-Baese, L. & Keilholz, S. (ISMRM2023) Manual registration and customized template for rodent fMRI data spatial normalization. https://www.ismrm.org/23/program-files/D-19.htm.

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