560-03-006 ISMRM Abstract

Measurement of myocardial extracellular volume fraction and cardiomyocyte diameter before after aortic valve replacement

Primary: Cardiovascular - Myocardium

Secondary: Contrast Mechanisms - Contrast Agents

560-03-006 · Congenital Heart Disease, Valves, and Vessels · Wednesday, 13 May, 1:40 PM–2:35 PM · Digital Posters Row A

Keywords: Water exchange Contrast enhanced MRI Aortic stenosis Cardiomyocyte hypertrophy Extracellular volume fraction

Accepted

Noor Sharrack¹, Alex Makins², John D Biglands², Peter Kellman³, Sven Plein¹, David L Buckley ¹

¹Biomedical Imaging Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom

²Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom

³NHLBI, NIH, Bethesda, Maryland, United States of America

Presenting Author: David L Buckley

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References

1. Everett RJ, Treibel TA, Fukui M, et al. Extracellular Myocardial Volume in Patients With Aortic Stenosis. J Am Coll Cardiol 2020;75(3):304-316 doi:10.1016/j.jacc.2019.11.032. [doi]

2. Coelho-Filho OR, Mongeon FP, Mitchell R, et al. Role of transcytolemmal water-exchange in magnetic resonance measurements of diffuse myocardial fibrosis in hypertensive heart disease. Circ Cardiovasc Imaging 2013;6(1):134-141 doi:10.1161/CIRCIMAGING.112.979815. [doi]

3. Sharrack N, Biglands JD, Broadbent DA, et al. The impact of water exchange on estimates of myocardial extracellular volume calculated using contrast enhanced T1 measurements: A preliminary analysis in patients with severe aortic stenosis. Magn Reson Med 2024;91(4):1637-1644 doi:10.1002/mrm.29956. [doi]

4. Krayenbuehl HP, Hess OM, Monrad ES, Schneider J, Mall G, Turina M. Left ventricular myocardial structure in aortic valve disease before, intermediate, and late after aortic valve replacement. Circulation 1989;79(4):744-755 doi:10.1161/01.CIR.79.4.744. [doi]

5. Coelho-Filho OR, Shah RV, Mitchell R, et al. Quantification of cardiomyocyte hypertrophy by cardiac magnetic resonance: implications for early cardiac remodeling. Circulation 2013;128(11):1225-1233 doi:10.1161/CIRCULATIONAHA.112.000438. [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/560-03-006