631-03-013 / 631-03-013 ISMRM Abstract

High-fidelity mesoscale diffusion MRI at NexGen 7T using gSlider with integrated B₁⁺ and T₁ correction

Primary: Diffusion - Diffusion Acquisition

Secondary: Acquisition & Reconstruction - Non-AI methods

631-03-013 · Diffusion Acquisition and Reconstruction · Thursday, 14 May, 4:00 PM–5:36 PM · Roof Terrace

Keywords: Connectome gradient Ultra-High Field (UHF) B1 inhomogeneity Mesoscale Diffusion-weighted imaging (DWI)

Accepted

Jiazheng Zhou¹, Xiaozhi Cao², Zheren Zhu¹, Yurui Qian ¹, Mengze Gao², Oleksandr Khegai³, Erica B Walker^3,4, Alexander J Beckett^3,4, Yang Yang¹, Kawin Setsompop², David Feinberg^3,4, An T Vu^1,5, Congyu Liao¹

¹Department of Radiology and Biomedical Imaging, University Of California, San Francisco (UCSF), United States of America

²Department of Radiology, Stanford University, Stanford, United States of America

³Helen Wills Neuroscience Institute, University of California, Berkeley, United States of America

⁴Advanced MRI Technologies, LLC, Sebastopol, United States of America

⁵Radiology Service, San Francisco Veteran Affairs Health Care System, San Francisco, United States of America

Presenting Author: Yurui Qian

Synopsis

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References

1. Feinberg DA, Beckett AJS, Vu AT, Stockmann J, Huber L, Ma S, et al. Next-generation MRI scanner designed for ultra-high-resolution human brain imaging at 7 Tesla. Nat Methods. 2023 Dec;20(12):2048–57.

2. 2. Wu W, Poser BA, Douaud G, Frost R, In MH, Speck O, et al. High-resolution diffusion MRI at 7T using a three-dimensional multi-slab acquisition. NeuroImage. 2016 Dec 1;143:1–14.

3. Wang F, Dong Z, Tian Q, Liao C, Fan Q, Hoge WS, et al. In vivo human whole-brain Connectom diffusion MRI dataset at 760 µm isotropic resolution. Sci Data. 2021 Apr 29;8(1):122.

4. Setsompop K, Fan Q, Stockmann J, Bilgic B, Huang S, Cauley SF, et al. High-resolution in vivo diffusion imaging of the human brain with generalized slice dithered enhanced resolution: Simultaneous multislice (gSlider-SMS). Magnetic Resonance in Medicine. 2018;79(1):141–51.

5. Cao X, Liao C, Beckett AJS, Vu AT, Ma S, Schauman S, et al. Rapid mesoscale 3D whole-brain MRF in the Next-Generation 7T brain scanner: challenges and advantages. In: Proc Intl Soc Mag Reson Med 31 (2023). p. 1421.

6. Marques JP, Kober T, Krueger G, van der Zwaag W, Van de Moortele PF, Gruetter R. MP2RAGE, a self bias-field corrected sequence for improved segmentation and T1-mapping at high field. NeuroImage. 2010 Jan 15;49(2):1271–81.

7. Jenkinson M, Beckmann CF, Behrens TEJ, Woolrich MW, Smith SM. FSL. NeuroImage. 2012 Aug 15;62(2):782–90.

8. Tournier JD, Smith R, Raffelt D, Tabbara R, Dhollander T, Pietsch M, et al. MRtrix3: A fast, flexible and open software framework for medical image processing and visualisation. NeuroImage. 2019 Nov 15;202:116137.

9. Jenkinson M, Smith S. A global optimisation method for robust affine registration of brain images. Medical Image Analysis. 2001 June 1;5(2):143–56.

10. Liao C, Stockmann J, Tian Q, Bilgic B, Arango NS, Manhard MK, et al. High-fidelity, high-isotropic-resolution diffusion imaging through gSlider acquisition with and T1 corrections and integrated ΔB0/Rx shim array. Magnetic Resonance in Medicine. 2020;83(1):56–67.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/631-03-013