Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
667-04-001 ISMRM Abstract

Rapid Multiparametric UTE MRI for In Vivo Compositional Assessment of Human Bone

Accepted
Soo Hyun Shin 1, Jiaji Wang1,2, James Lo1, Jiayang Wu1,3, Arya A Suprana1, Jiyo S Athertya1, Eric Y Chang1,4, Monica Guma1, Jiang Du1,4, Yajun Ma1
1University of California, Berkeley, United States of America
2Department of Radiology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, China
3Medical Imaging Center, The First Affiliated Hospital of Jinan University, Guangzhou, China
4Radiology Service, VA San Diego Healthcare System, La Jolla, California, San Diego, United States of America
Presenting Author: Soo Hyun Shin

Synopsis

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References

1. D.B. Burr, The contribution of the organic matrix to bone’s material properties. Bone. 2002;31:8-11.
2. Sheu et al., The role of bone marrow and visceral fat on bone metabolism. Curr Osteoporo Reports. 2011;9:67-75.
3. Giangregorio et al. FRAX underestimates fracture risk in patients with diabetes. J Bone Miner Res. 2012;27(2):301-308.
4. Du et al., Takahashi A, Chung CB, Bydder GM. Qualitative and quantitative ultrashort echo time (UTE) imaging of cortical bone. J Magn Reson. 2010;207(2):304-311.
5. Shin et al., UTE MRI technical developments and applications in osteoporosis: a review. Front Endocrinol. 2015;16:1510010.
6. Ma et al. Quantitative magnetization transfer ultrashort echo time imaging using a time-efficient 3D multispoke Cones sequence. Magn Reson Med. 2018;79(2):692-700.
7. Ma et al., Trabecular bone imaging using a 3D adiabatic inversion recovery prepared ultrashort echo time cones sequence at 3T. Magn Reson Med. 2020;83:1640-1651.
8. Shin et al., Spectrally-selective and interleaved water imaging and fat imaging (siWIFI). Magn Reson Med. 2025;93:1556-1567.
9. Patsch et al., Increased cortical porosity in type 2 diabetic postmenopausal women with fragility fractures. JBMR. 2013;28:313-324.
10. Daskareh et al., Fast volumetric imaging of bone using a three-dimensional short TR adiabatic inversion recovery ultrashort echo time (STAIR-UTE) sequence. NMR Biomed. 2025;38:e70102.
11. A.L. Boskey, Bone composition: relationship to bone fragility and antiosteoporotic drug effects. BoneKEy Reports. 2013;2:447.

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