Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
668-04-010 ISMRM Abstract

Oxygen-Enhanced T1 shortening of lung using Radial UTE VFA MRI

Primary: Body - Lung
Secondary: Contrast Mechanisms - Oxygenation
668-04-010 · Pulse Sequences: Design and Optimization · Thursday, 14 May, 2:35 PM–3:30 PM · Digital Posters Row I
Keywords: Ultra-short Echo Time (UTE) Variable Flip Angles Oxygen-enhanced Tissue Oxygenation T1 shortening
Accepted
Saman Khodaei1, Abhilash Kizhakke Puliyakote2, Conner J Wharff2, keegan R Staab3, Andrew D Hahn2, Sean B Fain 1,2
1Roy J. Carver Department of Biomedical Engineering, University of Iowa, Iowa City, United States of America
2Department of Radiology, University of Iowa, Iowa City, United States of America
3Carver College of Medicine, University of Iowa, Iowa City, Iowa, University of Iowa, Iowa City, United States of America
Presenting Author: Sean B Fain

Synopsis

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References

1. Alamidi, D. F., Morgan, A. R., Hubbard Cristinacce, P. L., Nordenmark, L. H., Hockings, P. D., Lagerstrand, K. M., Parker, G. J. M. (2015). COPD Patients Have Short Lung Magnetic Resonance T1 Relaxation Time. COPD: Journal of Chronic Obstructive Pulmonary Disease, 13(2), 153–159. https://doi.org/10.3109/15412555.2015.1048851 [doi]
2. Kruger, S. J., Nagle, S. K., Couch, M. J., Ohno, Y., Albert, M., & Fain, S. B. (2016). Functional imaging of the lungs with gas agents. Journal of Magnetic Resonance Imaging, 43(2), 295-315.
3. Ohno, Y., Chen, Q., & Hatabu, H. (2001). Oxygen-enhanced magnetic resonance ventilation imaging of lung. European journal of radiology, 37(3), 164-171.
4. Ohno, Y., & Hatabu, H. (2007). Basics concepts and clinical applications of oxygen-enhanced MR imaging. European journal of radiology, 64(3), 320-328.
5. Bhattacharya, I., Ramasawmy, R., Javed, A., Chen, M. Y., Benkert, T., Majeed, W., ... & Campbell‐Washburn, A. E. (2021). Oxygen‐enhanced functional lung imaging using a contemporary 0.55 T MRI system. NMR in Biomedicine, 34(8), e4562.
6. Jobst, B. J., Triphan, S. M., Sedlaczek, O., Anjorin, A., Kauczor, H. U., Biederer, J., ... & Wielpütz, M. O. (2015). Functional lung MRI in chronic obstructive pulmonary disease: comparison of T1 mapping, oxygen-enhanced T1 mapping and dynamic contrast enhanced perfusion. PLoS One, 10(3), e0121520.
7. Shen, Y., Goerner, F. L., Snyder, C., Morelli, J. N., Hao, D., Hu, D., ... & Runge, V. M. (2015). T1 relaxivities of gadolinium-based magnetic resonance contrast agents in human whole blood at 1.5, 3, and 7 T. Investigative radiology, 50(5), 330-338.
8. Szomolanyi, P., Rohrer, M., Frenzel, T., Noebauer-Huhmann, I. M., Jost, G., Endrikat, J., ... & Pietsch, H. (2019). Comparison of the relaxivities of macrocyclic gadolinium-based contrast agents in human plasma at 1.5, 3, and 7 T, and blood at 3 T. Investigative radiology, 54(9), 559-564.
9. Khodaei, S., Puliyakote, A. K., Wharff, C., McIntosh, M., Meyer, R., Aboderin, O., ... & Fain, S. T1 Mapping in the Lungs using a Variable Flip Angle Approach with UTE-MRI.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/668-04-010