Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
663-01-011 ISMRM Abstract

Repeatability of Time-Dependent Diffusion MRI for Quantitative Assessment of Hepatic Microstructure

Primary: Diffusion - Microstructure
Secondary: Body - Liver
663-01-011 · Diffusion MRI, Iron Quantification, and Steatosis in Human and Preclinical Studies · Thursday, 14 May, 8:30 AM–9:25 AM · Digital Posters Row D
Keywords: Repeatability Microstructural parameters OGSE diffusion imaging Diffusion-weighted imaging (DWI)
Accepted
CUNJING ZHENG 1, Jinhuan Song2, Yinji Piao1, Xuhao Zhu2, Jun Peng3, Rongli Zhang4,5, Ming Huang6, zhongbiao xu7
1Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University,, Guangzhou, China
2Department of Radiology, Fuyong People’s Hospital, Shenzhen, China
3Clinical and Technical Support, Philips Healthcare (Guangzhou), Guangzhou, China
4The Chinese University of Hong Kong, Shatin, Hong Kong
5Department of Diagnostic Radiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, Hong Kong
6Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
7Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, GuangDong, Guangzhou, China
Presenting Author: CUNJING ZHENG

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References

1. Reynaud O. Time-dependent diffusion MRI in cancer: tissue modeling and applications[J]. Frontiers in Physics, 2017, 5: 58.
2. Ba R, Wang X, Zhang Z, Li Q, Sun Y, Zhang J, Wu D. Diffusion-time dependent diffusion MRI: effect of diffusion-time on microstructural mapping and prediction of prognostic features in breast cancer. Eur Radiol. 2023 Sep;33(9):6226-6237. doi: 10.1007/s00330-023-09623-y. Epub 2023 Apr 18. PMID: 37071169. [doi] [pmid]
3. Wu D, Jiang K, Li H, Zhang Z, Ba R, Zhang Y, Hsu YC, Sun Y, Zhang YD. Time-Dependent Diffusion MRI for Quantitative Microstructural Mapping of Prostate Cancer. Radiology. 2022 Jun;303(3):578-587. doi: 10.1148/radiol.211180. Epub 2022 Mar 8. PMID: 35258368. [doi] [pmid]
4. Jiang X, Xu J, Gore JC. Mapping hepatocyte size in vivo using temporal diffusion spectroscopy MRI. Magn Reson Med. 2020 Nov;84(5):2671-2683. doi: 10.1002/mrm.28299. Epub 2020 Apr 25. PMID: 32333469; PMCID: PMC7402009. [doi] [pmid]
5. Jiang X, Li H, Devan SP, Gore JC, Xu J. MR cell size imaging with temporal diffusion spectroscopy. Magn Reson Imaging. 2021 Apr;77:109-123. doi: 10.1016/j.mri.2020.12.010. Epub 2020 Dec 16. PMID: 33338562; PMCID: PMC7878439. [doi] [pmid]
6. Zhang L, Long X, Chen L, Han X, Zhang X, Sun P, Yang Y, Fan J, Wang J, Lei Z, Liang B, Liu X, Shi H. Detecting Cellular Microstructural Changes of Liver Fibrosis with Time-Dependent Diffusion MRI. Radiology. 2024 Oct;313(1):e240343. doi: 10.1148/radiol.240343. PMID: 39352282. [doi] [pmid]
7. 7.Zheng CJ, Xiao BH, Huang H, Zhou N, Yan TY, Wáng YXJ. Bi-exponential fitting excluding b=0 data improves the scan-rescan stability of liver IVIM parameter measures and particularly so for the perfusion fraction. Quant Imaging Med Surg. 2022 Jun;12(6):3288-3299. doi: 10.21037/qims-2022-02. PMID: 35655827; PMCID: PMC9131351. [doi] [pmid]

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http://echo.ismrm.org/p/ISMRM2026/663-01-011