570-08-229 ISMRM Abstract

Multiparametric mapping of tumor hypoxia in a human neuroendocrine tumor mouse model

Primary: Preclinical Animal & in vitro MR - Biomarkers

Secondary: Contrast Mechanisms - Oxygenation

570-08-229 · Preclinical · Wednesday, 13 May, 4:00 PM–4:55 PM · Traditional Posters | Exhibition Hall

Keywords: Preclinical Cancer Tumor response evaluation Multiparametric MRI Hypoxia

Accepted

Mikael Montelius ¹, Lukas Lundholm^1,2, Maja C Sohlin^1,2, Oscar Jalnefjord^1,2, Eva Forssell-Aronsson^1,2, Maria Ljungberg^1,2

¹Department of Medical Radiation Sciences, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

²Department of Biomedical Engineering and Medical Physics, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden

Presenting Author: Mikael Montelius

Synopsis

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References

1. Perez RC, et al. Functional imaging of hypoxia: PET and MRI. Cancers. 2023(15):3336.

2. O’Connor JPB, Robinson SP, Waterton JC. Imaging tumour hypoxia with oxygen-enhanced MRI and BOLD MRI. Br J Radiol. 2019(92):20180642.

3. Yankeelov TE, et al. Quantitative pharmacokinetic analysis of DCE-MRI data without an arterial input function: a reference region model. Magn Reson Imaging. 2005(23):519-529.

4. Mo T, et al. Quantification of tumor hypoxia through unsupervised modelling of consumption and supply hypoxia MR imaging in breast cancer. Cancers. 2022(14):1326.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/570-08-229