Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
363-04-006 ISMRM Abstract

Amyloid Detection-Derived Analysis (ADDA): A QSM Framework for Quantification of Early Alzheimer’s Disease in Mice

Primary: Analysis Methods - Visualization
Secondary: Neuro - Alzheimer's Disease
363-04-006 · From Iron to Intelligence: Quantitative Imaging and AI in Brain Disorders · Monday, 11 May, 2:45 PM–3:40 PM · Digital Posters Row D
Keywords: Quantitative Susceptibility mapping Beta-amyloid Detection ADDA Framewrok Beta-amyloid plaque loading Beta-amyloid Plaque Probability Map
Accepted
Jie Chen1, Zhuoheng Liu1, Xinyue Han1, Hongbo Wu1, Nataliya Tod1, Juan Liu1, Nian Wang 1,2
1University of Texas Southwestern Medical Center, Dallas, United States of America
2Peter O'Donnell Jr. Brain Institute, University of Texas Southwestern​ Medical Center, Dallas, United States of America
Presenting Author: Nian Wang

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References

1. Chen, J., Han, X., Liu, Z., Zhou, C., Hu, R., Tabassam, S., ... & Wang, N. (2025). Detecting Beta-amyloid Plaque via Low Rank Based Orthogonal Projection and Spatial-spectrum Detector Using High-resolution Quantitative Susceptibility Mapping for Preclinical Studies. IEEE Transactions on Biomedical Engineering. DOI: 10.1109/TBME.2025.3614233 [doi]
2. Wang N, Cofer G, Anderson RJ, Qi Y, Liu C, Johnson GA. Accelerating quantitative susceptibility imaging acquisition using compressed sensing. Phys Med Biol. 2018;63 (24):245002. doi:10.1088/1361-6560/aaf15d [doi]
3. Wang N, Zhuang J, Wei H, Dibb R, Qi Y, Liu C. Probing demyelination and remyelination of the cuprizone mouse model using multimodality MRI. Journal of Magnetic Resonance Imaging. 2019;50(6):1852-1865. doi:10.1002/jmri.26758 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/363-04-006