Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
631-03-009 / 631-03-009 ISMRM Abstract

200 mT/m ultra-high gradient cardiac diffusion tensor imaging: validation in healthy participants and cardiomyopathy cohorts

Accepted
Ling Chen1, Xianling Qian1, Zhuolin Liu1, Jili Chen1, Christopher Nguyen2, Caixia Fu3, xiaoming Liu4, Yuchi Liu 5, Yishi Wang4, Yunzhu Wu6, Jing An3, Danielle Kara2, Dingheng Mai2, Moses P Cook2, Zachary Player2, Xuhao Song1, Yinyin Chen1, Hang Jin1, Mengsu Zeng1
1Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai, China
2Cardiovascular Innovation Research Center, Heart Vascular Thoracic Institute, Cleveland Clinic, Cleveland, United States of America
3MR Application Development, Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China
4Research Collaboration Team, Siemens Healthineers, Beijing, China
5Cardiovascular MR R&D Collaborations, Siemens Medical Solutions USA, Inc., Cleveland, United States of America
6Research Collaboration Team, Siemens Healthineers, Shanghai, China
Presenting Author: Yuchi Liu

Synopsis

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References

1. Khalique Z, Ferreira PF, Scott AD, Nielles-Vallespin S, Firmin DN, Pennell DJ. Diffusion tensor cardiovascular magnetic resonance imaging: A clinical perspective. JACC. Cardiovascular imaging 2020;13:1235-1255. doi: https://doi.org/10.1016/j.jcmg.2019.07.016 [doi]
2. Nielles-Vallespin S, Khalique Z, Ferreira PF, de Silva R, Scott AD, Kilner P, et al. Assessment of myocardial microstructural dynamics by in vivo diffusion tensor cardiac magnetic resonance. Journal of the American College of Cardiology 2017;69:661-676. doi: https://doi.org/10.1016/j.jacc.2016.11.051 [doi]
3. Nielles‐Vallespin S, Scott A, Ferreira P, Khalique Z, Pennell D, Firmin D. Cardiac Diffusion: Technique and Practical Applications. Journal of Magnetic Resonance Imaging 2020;52:348-368. doi: https://doi.org/10.1002/jmri.26912 [doi]
4. Dall'Armellina E, Ennis DB, Axel L, Croisille P, Ferreira PF, Gotschy A, et al. Cardiac diffusion-weighted and tensor imaging: A consensus statement from the special interest group of the society for cardiovascular magnetic resonance. Journal of Cardiovascular Magnetic Resonance: Official Journal of the Society for Cardiovascular Magnetic Resonance 2025;27:101109. doi: https://doi.org/10.1016/j.jocmr.2024.101109 [doi]
5. Nguyen CT, Christodoulou AG, Coll-Font J, Ma S, Xie Y, Reese TG, et al. Free-breathing diffusion tensor MRI of the whole left ventricle using second-order motion compensation and multitasking respiratory motion correction. Magnetic Resonance in Medicine 2021;85:2634-2648. doi: https://doi.org/10.1002/mrm.28611 [doi]
6. Stoeck CT, von Deuster C, Genet M, Atkinson D, Kozerke S. Second-order motion-compensated spin echo diffusion tensor imaging of the human heart. Magnetic Resonance in Medicine 2016;75:1669-1676. doi: https://doi.org/10.1002/mrm.25784 [doi]
7. Kara D, Liu Y, Chen S, Garrett T, Younis A, Sugawara M, et al. In vivo cardiac diffusion tensor imaging on an MR system featuring ultrahigh performance gradients with 200 mT/m maximum gradient strength. Magnetic Resonance in Medicine 2025;93:673-688. doi: https://doi.org/10.1002/mrm.30308 [doi]

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