Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
363-02-009 ISMRM Abstract

Modular Level Alterations Of Structural-Functional Connectivity Coupling in type 2 diabetes mellitus

Primary: Brain Function and fMRI - Functional Connectivity
Secondary: Diffusion - Tractography
363-02-009 · All About Diffusion · Monday, 11 May, 9:15 AM–10:10 AM · Digital Posters Row D
Keywords: Functional Connectivity Type 2 diabetes mellitus Graph theory analysis 3.0T magnetic resonance imaging Structural-Functional Coupling
Accepted
Jiahao Yan1, Jing Zhang 2,3,4,5
1Lanzhou University Second Hospital, Lanzhou University, Lanzhou, China
2The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, China
3Department of Magnetic Resonance, Lanzhou, China
4Gansu Province Clinical Research Center for Functional and Molecular Imaging, Lanzhou, China, Department of Magnetic Resonance, Lanzhou, China
5Gansu Province Clinical Research Center for Functional and Molecular Imaging, Lanzhou, China, Department of Magnetic Resonance, Lanzhou, China
Presenting Author: Jing Zhang

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References

1. He D, Hao Z, Zhao M, Li M, Hou N, Yu Y, et al. Structural and functional brain abnormal alteration in patients with type 2 diabetes mellitus: A coordinate-based meta-analysis. Transl Psychiatry. 2025;15:269. doi:10.1038/s41398-025-03488-z. [doi]
2. Li J, Zhang Q, Wang J, Liu L. Network efficiency of functional brain connectomes altered in type 2 diabetes patients with and without mild cognitive impairment. Diabetol Metab Syndr. 2024;16:247. doi:10.1186/s13098-024-01484-9. [doi]
3. Ni W, Zhang Z, Wang Q, Li H, Zeng X, Tan J, et al. Altered brain functional network connectivity and topology in type 2 diabetes mellitus. Front Neurosci. 2025;19:1472010. doi:10.3389/fnins.2025.1472010. [doi]
4. Popp JL, Thiele JA, Faskowitz J, Seguin C, Sporns O, Hilger K. Structural-functional brain network coupling predicts human cognitive ability. Neuroimage. 2024;290:120563. doi:10.1016/j.neuroimage.2024.120563. [doi]
5. Lu W, Huang X, Shen D, Wang K, Wang J, Diao Z, et al. Potential compensatory mechanism for cognitive impairment in type 2 diabetes and prediabetes: altered structure-function coupling. Front Endocrinol (Lausanne). 2025;16:1491377. doi:10.3389/fendo.2025.1491377. [doi]
6. Hu S, Hao Z, Li M, Zhao M, Wen J, Gao Y, et al. Resting-state abnormalities in functional connectivity of the default mode network in migraine: a meta-analysis. Front Neurosci. 2023;17:1136790. doi:10.3389/fnins.2023.1136790. [doi]
7. Normand F, Gajwani M, Côté DC, Allard A. NBS-SNI, an extension of the network-based statistic: abnormal functional connections between important structural actors. Netw Neurosci. 2024;8(1):44–80. doi:10.1162/netn_a_00344. [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/363-02-009