Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
461-04-001 ISMRM Abstract

Diffusion-weighted MRI of Abdominal Lymph-Nodes: Comparison between Crohn’s Disease and Healthy Volunteers

Primary: Body - Digestive
Secondary: Diffusion - Diffusion Acquisition
461-04-001 · Quantitative MRI Across the Body · Tuesday, 12 May, 2:35 PM–3:30 PM · Digital Posters Row B
Keywords: Treatment Response Lymph node Abdominal MRI Apparent Diffusion Coefficient (ADC) Crohns Disease
Accepted
Maria O Ralph 1,2, Iyad Naim3, Gordon W Moran2,4, Caroline Hoad1, Penny Gowland1,5
1Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, United Kingdom
2The School of Medicine, University of Nottingham, Nottingham, United Kingdom
3Motilent, London, United Kingdom
4Nottingham Digestive Diseases Centre Biomedical Research Unit, University of Nottingham, Nottingham, United Kingdom
5NIHR Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, United Kingdom
Presenting Author: Maria O Ralph

Synopsis

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References

1. Maconi, G. & Di Sabatino, A. & Ardizzone, S. & Greco, S. & Colombo, E. & Russo, A. & Cassinotti, A. & Casini, V. & Corazza, GR. & Bianchi Porro, G. (2005). Prevalence and clinical significance of sonographic detection of enlarged regional lymph nodes in Crohn's disease. Scand J Gastroenterol, Nov;40(11), 1328-33. PMID: 16243717. [pmid]
2. Makanyanga, J.C., Pendsé, D., Dikaios, N. et al. (2014). Evaluation of Crohn’s disease activity: Initial validation of a magnetic resonance enterography global score (MEGS) against faecal calprotectin. Eur Radiol, 24, 277–287. https://doi.org/10.1007/s00330-013-3010-z [doi]
3. Tolan D.J., Greenhalgh R., Zealley I.A., Halligan S., Taylor S.A. (2010). MR enterographic manifestations of small bowel Crohn disease. Radiographics, Mar;30(2), 367-84. https://doi.org/10.1148/rg.302095028. PMID: 20228323. [doi] [pmid]
4. Kwee, T. C., Takahara, T., Luijten, P. R., & Nievelstein, R. A. J. (2010). ADC measurements of lymph-nodes: Inter- and intra-observer reproducibility study and an overview of the literature. European Journal of Radiology, 75(2), 215–220. https://doi.org/10.1016/j.ejrad.2009.03.026 [doi]
5. Williams H., Hoad C., Scott R., Aithal G., Marciani L., Moran G., Gowland, P. (2019) P025: Comparison of abdominal lymph-nodes between healthy volunteers and patients with Crohn’s disease. Journal of Crohn's and Colitis, 13(1), S098–S099. https://doi.org/10.1093/ecco-jcc/jjy222.149 [doi]
6. Takahara, T., Imai, Y., Yamashita, T., Yasuda, S., Nasu, S., & Van Cauteren, M. (2004). Diffusion weighted whole body imaging with background body signal suppression (DWIBS): Technical improvement using free breathing, STIR and high resolution 3D display. Radiation Medicine, 22(4), 275–282. PMID: 15468951 [pmid]
7. McAuliffe, M. J., Lalonde, F. M., McGarry, D., Gandler, W., Csaky, K., & Trus, B. L. (2001). Medical image processing, analysis & visualization in clinical research. In Proceedings of the 14th IEEE Symposium on Computer-Based Medical Systems (CBMS 2001) (pp. 381–386). IEEE. https://doi.org/10.1109/CBMS.2001.941749 [doi]
8. Virtanen, P., Gommers, R., Oliphant, T.E. et al. (2020). SciPy 1.0: fundamental algorithms for scientific computing in Python. Nat Methods, 17, 261–272. https://doi.org/10.1038/s41592-019-0686-2 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/461-04-001