431-01-009 / 431-01-009 ISMRM Abstract

In-Vivo Metabolic Profiling of Meningiomas Using 7T MRSI

Primary: Contrast Mechanisms - Spectroscopy

Secondary: Neuro - Tumors

431-01-009 · From Microstructure to Metabolism: Next-Generation MRI for Brain Tumors · Tuesday, 12 May, 8:20 AM–9:56 AM · Roof Terrace

Keywords: 7 Tesla Metabolic imaging Meningiomas Magnetic resonance spectroscopic imaging

Accepted

Philipp Lazen ^1,2, Sara Huskic^1,2, Cornelius Cadrien^1,2, Rebeka Rumbak^2,3, Fabian Winter¹, Bernhard Strasser², Lukas Hingerl², Thomas Roetzer-Pejrimovsky^2,4, Johannes Leitner², Julia Furtner², Wolfgang Bogner^2,5, Georg Widhalm¹, Karl Rössler^1,2,5, Gilbert Hangel^1,2

¹Department of Neurosurgery, Medical University of Vienna, Vienna, Austria

²Medical University of Vienna, Vienna, Austria

³Department of Neurology, Medical University of Vienna, Vienna, Austria

⁴Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, Vienna, Austria

⁵Christian Doppler Laboratory for MR Imaging Biomarkers (BIOMAK), Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria

Presenting Author: Philipp Lazen

Synopsis

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References

1. Ostrom, Q. T.; Cioffi, G.; Waite, K.; Kruchko, C.; Barnholtz-Sloan, J. S. CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2014–2018. Neuro-Oncol. 2021, 23 (Suppl 3), iii1. https://doi.org/10.1093/neuonc/noab200. [doi]

2. Hingerl, L.; Strasser, B.; Moser, P.; Hangel, G.; Motyka, S.; Heckova, E.; Gruber, S.; Trattnig, S.; Bogner, W. Clinical High-Resolution 3D-MR Spectroscopic Imaging of the Human Brain at 7 T. Invest. Radiol. 2020, 55 (4), 239–248. https://doi.org/10.1097/RLI.0000000000000626. [doi]

3. Hangel, G.; Niess, E.; Lazen, P.; Bednarik, P.; Bogner, W.; Strasser, B. Emerging Methods and Applications of Ultra-High Field MR Spectroscopic Imaging in the Human Brain. Anal. Biochem. 2022, 638, 114479. https://doi.org/10.1016/j.ab.2021.114479. [doi]

4. Tamrazi, B.; Shiroishi, M. S.; Liu, C.-S. J. Advanced Imaging of Intracranial Meningiomas. Neurosurg. Clin. N. Am. 2016, 27 (2), 137–143. https://doi.org/10.1016/j.nec.2015.11.004. [doi]

5. Cubillos, S.; Obregón, F.; Vargas, M. F.; Salazar, L. A.; Lima, L. Taurine Concentration in Human Gliomas and Meningiomas: Tumoral, Peritumoral, and Extratumoral Tissue. Adv. Exp. Med. Biol. 2006, 583, 419–422. https://doi.org/10.1007/978-0-387-33504-9_47. [doi]

6. MATLAB, 2017.

7. Provencher, S. W. Automatic Quantitation of Localized in Vivo 1H Spectra with LCModel. NMR Biomed. 2001, 14 (4), 260–264. https://doi.org/10.1002/nbm.698. [doi]

8. Ijare, O. B.; Hambarde, S.; Brasil da Costa, F. H.; Lopez, S.; Sharpe, M. A.; Helekar, S. A.; Hangel, G.; Bogner, W.; Widhalm, G.; Bachoo, R. M.; Baskin, D. S.; Pichumani, K. Glutamine Anaplerosis Is Required for Amino Acid Biosynthesis in Human Meningiomas. Neuro-Oncol. 2022, 24 (4), 556–568. https://doi.org/10.1093/neuonc/noab219. [doi]

9. Ijare, O. B.; Powell, S. Z.; Baskin, D. S.; Pichumani, K. TMET-38. BIOCHEMICAL CHARACTERIZATION OF PSAMMOMATOUS MENINGIOMA USING MAGNETIC RESONANCE SPECTROSCOPY. Neuro-Oncol. 2024, 26 (Supplement_8), viii296. https://doi.org/10.1093/neuonc/noae165.1176. [doi]

10. Sivaparvathi, M.; McCutcheon, I.; Sawaya, R.; Nicolson, G. L.; Rao, J. S. Expression of Cysteine Protease Inhibitors in Human Gliomas and Meningiomas. Clin. Exp. Metastasis 1996, 14 (4), 344–350. https://doi.org/10.1007/BF00123393. [doi]

11. Wang, J. Z.; Patil, V.; Landry, A. P.; Gui, C.; Ajisebutu, A.; Liu, J.; Saarela, O.; Pugh, S. L.; Won, M.; Patel, Z.; Yakubov, R.; Kaloti, R.; Wilson, C.; Cohen-Gadol, A.; Zaazoue, M. A.; Tabatabai, G.; Tatagiba, M.; Behling, F.; Almiron Bonnin, D. A.; Holland, E. C.; Kruser, T. J.; Barnholtz-Sloan, J. S.; Sloan, A. E.; Horbinski, C.; Chotai, S.; Chambless, L. B.; Gao, A.; Rebchuk, A. D.; Makarenko, S.; Yip, S.; Sahm, F.; Maas, S. L. N.; Tsang, D. S.; Rogers, C. L.; Aldape, K.; Nassiri, F.; Zadeh, G. Molecular Classification to Refine Surgical and Radiotherapeutic Decision-Making in Meningioma. Nat. Med. 2024, 1–11. https://doi.org/10.1038/s41591-024-03167-4. [doi]

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http://echo.ismrm.org/p/ISMRM2026/431-01-009