Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
664-02-010 ISMRM Abstract

Assessing myocardial ischemia-reperfusion injury in a pig model using rotating frame spin-lock MRI methods at 1.5 T

Primary: Cardiovascular - Inflammation, Infiltration
Secondary: Preclinical Animal & in vitro MR - Large Animals, Nonhuman Primates
664-02-010 · Large Animals · Thursday, 14 May, 9:25 AM–10:20 AM · Digital Posters Row E
Keywords: Contrast Mechanisms Ischemia Preclinical Cardiac MRI Large animal model
Accepted
Riku Kiviluoto 1, Minja Heikkilä1, Hanna Wang1, Jarkko Kuivalainen1, Anni Määttä1, Juho Liljeström, Mimmi Liukkonen2, Saara Sillanmäki2,3, Minna Husso2, Saija Puumalainen2, Sanna Tietäväinen2, Alexandru Schiopu4, Anna-Kaisa Ruotsalainen1, Seppo Ylä-Herttuala1, Elias Ylä-Herttuala1
1A.I. Virtanen Institute, University of Eastern Finland, Kuopio, Finland
2Diagnostic Imaging Centre, Kuopio University Hospital, Kuopio, Finland
3Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland
4Department of Translational Medicine, Lund University, Lund, Sweden
Presenting Author: Riku Kiviluoto

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References

1. M. Algoet et al., ‘Myocardial ischemia-reperfusion injury and the influence of inflammation’, Trends Cardiovasc. Med., vol. 33, no. 6, pp. 357–366, Aug. 2023, doi: 10.1016/j.tcm.2022.02.005. [doi]
2. S. A. Mirmojarabian et al., ‘Relaxation along Fictitious Field (RAFF) provide an appropriate alternative method for imaging chronic myocardial infarct without exogenous contrast media’, Interv. Cardiol., vol. 13, no. 5, p. 381, Aug. 2021, doi: 10.37532/1755-5310.2021.13(5).381-388. [doi]
3. Q. Wu et al., ‘Characterization of early myocardial inflammation in ischemia-reperfusion injury’, Front. Immunol., vol. 13, p. 1081719, Feb. 2023, doi: 10.3389/fimmu.2022.1081719. [doi]
4. D. Boll et al., ‘Cardiac MRI of differing ischemia and reperfusion times in a myocardial infarction pig model’, Sci. Rep., vol. 15, no. 1, p. 26270, Jul. 2025, doi: 10.1038/s41598-025-11390-3. [doi]
5. P. S. Rajiah, C. J. François, and T. Leiner, ‘Cardiac MRI: State of the Art’, Radiology, vol. 307, no. 3, p. e223008, May 2023, doi: 10.1148/radiol.223008. [doi]
6. J. Tourais et al., ‘Feasibility of relaxation along a fictitious field in the 2nd rotating frame (TRAFF2) mapping in the human myocardium at 3 T’, Front. Cardiovasc. Med., vol. 11, p. 1373240, Dec. 2024, doi: 10.3389/fcvm.2024.1373240. [doi]
7. E. Ylä-Herttuala, T. Vuorio, S. Kettunen, S. Laidinen, S. Ylä-Herttuala, and T. Liimatainen, ‘Lymphatic insufficiency leads to distinct myocardial infarct content assessed by magnetic resonance TRAFFn, T1ρ and T2 relaxation times.’, Sci. Rep., vol. 13, no. 1, p. 1579, Jan. 2023, doi: 10.1038/s41598-023-28219-6. [doi]
8. M. A. Khan et al., ‘The follow-up of progressive hypertrophic cardiomyopathy using magnetic resonance rotating frame relaxation times’, NMR Biomed., vol. 31, no. 2, p. e3871, 2018, doi: 10.1002/nbm.3871. [doi]

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http://echo.ismrm.org/p/ISMRM2026/664-02-010