Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
431-01-001 / 431-01-001 ISMRM Abstract

Optimization of a Dual Echo Multiband Dynamic Susceptibility Contrast MRI protocol with leakage estimation

Primary: Acquisition & Reconstruction - Pulse Sequence Design: Neuro
Secondary: Neuro - Tumors
431-01-001 · From Microstructure to Metabolism: Next-Generation MRI for Brain Tumors · Tuesday, 12 May, 8:20 AM–9:56 AM · Roof Terrace
431-01-001 · From Microstructure to Metabolism: Next-Generation MRI for Brain Tumors · Tuesday, 12 May, 8:20 AM–9:56 AM · Roof Terrace
Keywords: Brain DSC & DCE Perfusion Tumors
Accepted
Peter B Barker 1, Yuanqi Sun2, Shanshan Jiang1, Richard Leigh3
1Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, United States of America
2Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, United States of America
3Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, United States of America
Presenting Author: Peter B Barker

Synopsis

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References

1. Barker PB, Golay X, Zaharchuk G. Clinical Perfusion MRI: Techniques and Applications. 1st ed. Cambridge, UK: Cambridge University Press; 2013.
2. Boxerman JL, Quarles CC, Hu LS, Erickson BJ, Gerstner ER, Smits M, et al. Consensus recommendations for a dynamic susceptibility contrast MRI protocol for use in high-grade gliomas. Neuro Oncol. 2020;22(9):1262-75. doi: 10.1093/neuonc/noaa141. PubMed PMID: 32516388. [doi] [pmid]
3. Chakhoyan A, Leu K, Pope WB, Cloughesy TF, Ellingson BM. Improved Spatiotemporal Resolution of Dynamic Susceptibility Contrast Perfusion MRI in Brain Tumors Using Simultaneous Multi-Slice Echo-Planar Imaging. AJNR Am J Neuroradiol. 2018;39(1):43-5. Epub 20171026. doi: 10.3174/ajnr.A5433. PubMed PMID: 29074632. [doi] [pmid]
4. Bell LC, Does MD, Stokes AM, Baxter LC, Schmainda KM, Dueck AC, et al. Optimization of DSC MRI Echo Times for CBV Measurements Using Error Analysis in a Pilot Study of High-Grade Gliomas. AJNR Am J Neuroradiol. 2017;38(9):1710-5. Epub 20170706. doi: 10.3174/ajnr.A5295. PubMed PMID: 28684456. [doi] [pmid]
5. Newton AT, Pruthi S, Stokes AM, Skinner JT, Quarles CC. Improving Perfusion Measurement in DSC-MR Imaging with Multiecho Information for Arterial Input Function Determination. AJNR Am J Neuroradiol. 2016;37(7):1237-43. Epub 20160317. doi: 10.3174/ajnr.A4700. PubMed PMID: 26988812. [doi] [pmid]
6. Skinner JT, Moots PL, Ayers GD, Quarles CC. On the Use of DSC-MRI for Measuring Vascular Permeability. AJNR Am J Neuroradiol. 2016;37(1):80-7. Epub 20151001. doi: 10.3174/ajnr.A4478. PubMed PMID: 26427833. [doi] [pmid]
7. Wu J, Saindane AM, Zhong X, Qiu D. Simultaneous perfusion and permeability assessments using multiband multi-echo EPI (M2-EPI) in brain tumors. Magn Reson Med. 2019;81(3):1755-68. Epub 20181009. doi: 10.1002/mrm.27532. PubMed PMID: 30298595. [doi] [pmid]

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http://echo.ismrm.org/p/ISMRM2026/431-01-001