Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
569-01-002 ISMRM Abstract

Impact of Temperature Stability on Signal Quality in 200 µm Ex-vivo Human Brain MRI

Primary: Acquisition & Reconstruction - New Signal Preparation Schemes
Secondary: Neuro - Gray Matter
569-01-002 · Signal Modeling and Signal Preparation: Novel Approaches · Wednesday, 13 May, 8:20 AM–9:15 AM · Digital Posters Row J
Keywords: 7T Automated segmentation Image Quality Enhancement Quantitative Analysis Ex-vivo human brain
Accepted
Sanghoon Kim1,2,3,4, Pulkit Khandelwal5, Paul A Yushkevich5, Dan Benjamini4
1Military Traumatic Brain Injury Initiative (MTBI2), Bethesda, United States of America
2Uniformed Services University of the Health Sciences, Bethesda, United States of America
3The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, United States of America
4National Institute of Health, Bethesda, United States of America
5Department of Radiology, University of Pennsylvania, Philadelphia, United States of America
Presenting Author: Mihika Gangolli

Synopsis

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References

1. Birkl C, Langkammer C, Haybaeck J, et al. Temperature-induced changes of magnetic resonance relaxation times in the human brain: a postmortem study. Magn Reson Med. 2014 Apr;71(4):1575-80.
2. Kim S, Sakaie K, Blümcke I, et al. Whole-brain, ultra-high spatial resolution ex vivo MRI with off-the-shelf components. Magn Reson Imaging. 2021 Feb;76:39-48.
3. Khandelwal P, Duong MT, Sadaghiani S, et al. Automated deep learning segmentation of high-resolution 7 Tesla postmortem MRI for quantitative analysis of structure-pathology correlations in neurodegenerative diseases. Imaging Neurosci (Camb). 2024 May 8;2:1-30.
4. Khandelwal, Pulkit, et al. "Surface-based parcellation and vertex-wise analysis of ultra high-resolution ex vivo 7 tesla MRI in Alzheimer’s disease and related dementias." International Workshop on Machine Learning in Clinical Neuroimaging. Cham: Springer Nature Switzerland, 2024.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/569-01-002