Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
566-02-004 ISMRM Abstract

Impact of Cardiovascular-Kidney-Metabolic Syndrome on Dementia Subtypes and Brain Volume Changes

Primary: Neuro - Dementia
Secondary: Cardiovascular - Atherosclerosis
566-02-004 · MRI Markers of Dementia · Wednesday, 13 May, 9:15 AM–10:10 AM · Digital Posters Row G
Keywords: Dementia Magnetic resonance imaging Cardiovascular-kidney-metabolic syndrome Vascular dementia Epidemiology
Accepted
Yanfang Tan 1, Yu Li2, Wenbo Yang2, Lijun Song2, Boyan Xu3, Mingan Li2, Xiaoyan Bai2, Zhenghan Yang2, Zhenchang Wang2, Han Lv2, Hao Wang2, Min Li1
1Clinical Epidemiology and EBM Unit, Beijing Friendship Hospital, Capital Medical University, beijing, China
2Beijing Friendship Hospital, Capital Medical University, beijing, China
3MR Research, Beijing, China
Presenting Author: Yanfang Tan

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References

1. [1]Ndumele CE, Rangaswami J, Chow SL, Neeland IJ, Tuttle KR, Khan SS, et al. Cardiovascular-Kidney-Metabolic Health: A Presidential Advisory From the American Heart Association. Circulation. 2023;148:1606-35. doi: 10.1161/cir.0000000000001184 [doi]
2. [2] Aggarwal R, Ostrominski JW, Vaduganathan M. Prevalence of Cardiovascular-Kidney-Metabolic Syndrome Stages in US Adults, 2011-2020. JAMA. 2024;331:1858-60. doi: 10.1001/jama.2024.6892 [doi]
3. [3]World Health Organization. Dementia. World Health Organization. Published 2023. Accessed April 8, 2025. https://www.who.int/news-room/fact-sheets/detail/dementia.
4. Ng TP, Feng L, Nyunt MS, Feng L, Gao Q, Lim ML, et al. Metabolic Syndrome and the Risk of Mild Cognitive Impairment and Progression to Dementia: Follow-up of the Singapore Longitudinal Ageing Study Cohort. JAMA Neurol. 2016;73:456-63. doi: 10.1001/jamaneurol.2015.4899 [doi]
5. [5]Hendriks S, Ranson JM, Peetoom K, Lourida I, Tai XY, de Vugt M, et al. Risk Factors for Young-Onset Dementia in the UK Biobank. JAMA Neurol. 2024;81:134-42. doi: 10.1001/jamaneurol.2023.4929 [doi]
6. [6]Kurella M, Chertow GM, Fried LF, Cummings SR, Harris T, Simonsick E, et al. Chronic kidney disease and cognitive impairment in the elderly: the health, aging, and body composition study. J Am Soc Nephrol. 2005;16:2127-33. doi: 10.1681/asn.2005010005 [doi]
7. Newman AB, Fitzpatrick AL, Lopez O, Jackson S, Lyketsos C, Jagust W, et al. Dementia and Alzheimer's disease incidence in relationship to cardiovascular disease in the Cardiovascular Health Study cohort. J Am Geriatr Soc. 2005;53:1101-7. doi: 10.1111/j.1532-5415.2005.53360.x [doi]
8. Tai XY, Veldsman M, Lyall DM, Littlejohns TJ, Langa KM, Husain M, Ranson J, Llewellyn DJ, et al. Cardiometabolic multimorbidity, genetic risk, and dementia: a prospective cohort study. Lancet Healthy Longev. 2022;3:e428-36. doi: 10.1016/s2666-7568(22)00117-9 [doi]

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http://echo.ismrm.org/p/ISMRM2026/566-02-004