Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
369-03-013 ISMRM Abstract

Multi-parametric Metabolic Profiling in Ischemic Stroke Using 5T CEST-MRI with Advanced Quantitative Analysis (CESTQuant)

Primary: Contrast Mechanisms - CEST / APT / NOE
Secondary: Neuro - Stroke and Cerebrovascular Disorders
369-03-013 · Multiparametric MRI in Stroke · Monday, 11 May, 1:50 PM–2:45 PM · Digital Posters Row J
Keywords: CEST / APT / NOE Quantitative technology Ischemic Stroke CEST MRI Ultra-high field (UHF) MRI
Accepted
Lixin Du 1, Pan Wang1, Gen Yan2, Jing Yang3, Hai Lin3
1Shenzhen Longhua District Central Hospital, Shenzhen, China
2Xiamen Medical college, Xiamen, China
3Collaborative Innovation Department, United Imaging Healthcare, Shanghai, China
Presenting Author: Lixin Du

Synopsis

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References

1. Jones KM, Pollard AC, Pagel MD. Clinical applications of chemical exchange saturation transfer (CEST) MRI. J Magn Reson Imaging. 2018;47(1):11-27. doi: 10.1002/jmri.25838 [doi]
2. Sun PZ. Demonstration of accurate multi-pool chemical exchange saturation transfer MRI quantification - Quasi-steady-state reconstruction empowered quantitative CEST analysis. J Magn Reson. 2023;348:107379. doi: 10.1016/j.jmr.2023.107379 [doi]
3. Zaiss M, Jin T, Kim SG, Gochberg DF. Theory of chemical exchange saturation transfer MRI in the context of different magnetic fields. NMR Biomed. 2023;36(6):e4961. doi: 10.1002/nbm.4961 [doi]
4. Bie C, Ma Y, van Zijl PCM, Yadav NN, Xu X, Zheng H, Liang D, Zou C, Areta JL, Chen L, Zhou Y. In vivo imaging of glycogen in human muscle. Nat Commun. 2024;15(1):10826. doi: 10.1038/s41467-024-55132-x [doi]
5. Zhou J, Sun W, Li H, Song X, Xu D, Xu H. Application of 5T glutamate chemical exchange saturation transfer imaging in brain tumors: preliminary results. J Neurooncol. 2024;169(3):581-589. doi: 10.1007/s11060-024-04759-3 [doi]
6. Xiao G, Zhang XL, Wang SQ, Lai SX, Nie TT, Chen YW, Zhuang CY, Yan G, Wu RH. Quantitative separation of CEST effect by Rex-line-fit analysis of Z-spectra. Sci Rep. 2024;14(1):21471. doi: 10.1038/s41598-024-72141-4 [doi]
7. Xiao G, Zhang X, Tang H, Huang W, Chen Y, Zhuang C, Chen B, Yang L, Chen Y, Yan G, Wu R. Deep learning for dense Z-spectra reconstruction from CEST images at sparse frequency offsets. Front Neurosci. 2024;17:1323131. doi: 10.3389/fnins.2023.1323131 [doi]

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http://echo.ismrm.org/p/ISMRM2026/369-03-013