Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
367-04-003 ISMRM Abstract

Mapping Iron, Fibroblast Activation Protein, and Oxidative Stress in Ischemia-Reperfusion Injury with MRI and PET

Primary: Contrast Mechanisms - Molecular Imaging
Secondary: Cardiovascular - Myocardium
367-04-003 · Multimodality and Unconventional Cardiovascular MRI · Monday, 11 May, 2:45 PM–3:40 PM · Digital Posters Row H
Keywords: Fibrosis Quantitative Susceptibility Mapping (QSM) Myocardial infarction Oxidative stress
Accepted
Marina M Awad 1, Sophia Swago2,3, Chiara Camillo4, Diana Albino4, Elizabeth W Thompson1, Giovanni Ferrari4, Estibaliz Castillero4, Cory Tschabrunn5, Walter R Witschey2,3, Paco E Bravo2,5
1Department of Bioengineering, University of Pennsylvania, Philadelphia, United States of America
2Department of Radiology, University of Pennsylvania, Philadelphia, United States of America
3Center for Advanced Metabolic Imaging in Precision Medicine, Philadelphia, United States of America
4Department of Surgery, Columbia University, New York, United States of America
5Department of Medicine, University of Pennsylvania, Philadelphia, United States of America
Presenting Author: Marina M Awad

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References

1. Carrick D, Haig C, Ahmed N, et al. Myocardial Hemorrhage After Acute Reperfused ST-Segment-Elevation Myocardial Infarction: Relation to Microvascular Obstruction and Prognostic Significance. Circ Cardiovasc Imaging. 2016;9(1):e004148. doi:10.1161/CIRCIMAGING.115.004148 [doi]
2. Kali A, Kumar A, Cokic I, et al. Chronic Manifestation of Postreperfusion Intramyocardial Hemorrhage as Regional Iron Deposition. Circ Cardiovasc Imaging. 2013;6(2):218-228. doi:10.1161/CIRCIMAGING.112.000133 [doi]
3. Bing R, Dweck MR. Myocardial fibrosis: why image, how to image and clinical implications. Heart Br Card Soc. 2019;105(23):1832-1840. doi:10.1136/heartjnl-2019-315560 [doi]
4. Barton AK, Craig NJ, Loganath K, et al. Myocardial Fibroblast Activation After Acute Myocardial Infarction: A Positron Emission Tomography and Magnetic Resonance Study. J Am Coll Cardiol. 2025;85(6):578-591. doi:10.1016/j.jacc.2024.10.103 [doi]
5. Liu J, Liu T, De Rochefort L, et al. Morphology enabled dipole inversion for quantitative susceptibility mapping using structural consistency between the magnitude image and the susceptibility map. NeuroImage. 2012;59(3):2560-2568. doi:10.1016/j.neuroimage.2011.08.082 [doi]
6. Liu T, Khalidov I, De Rochefort L, et al. A novel background field removal method for MRI using projection onto dipole fields (PDF). NMR Biomed. 2011;24(9):1129-1136. doi:10.1002/nbm.1670 [doi]

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http://echo.ismrm.org/p/ISMRM2026/367-04-003