305-04-010 ISMRM Abstract

Exploring cuff-induced dynamics of skeletal muscle BOLD MRI in patients with peripheral artery disease and controls

Primary: Musculoskeletal - Muscle

Secondary: Cardiovascular - Flow

305-04-010 · MRI of Musculoskeletal Kinematics, Biomechanics, and Exercise · Monday, 11 May, 4:10 PM–6:00 PM · Ballroom West

Keywords: Perfusion Peripheral Arterial Disease BOLD Skeletal Muscle Imaging

Accepted

Jonathan Arvidsson ^1,2, Stefanie Eriksson^1,2, Oscar Jalnefjord^1,2, Edvin Johansson³, Joakim Nordanstig^4,5, Kerstin Lagerstrand^1,2

¹Department of Biomedical Engineering and Medical Physics, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden

²Department of Medical Radiation Sciences, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

³Antaros Medical, Gothenburg, Sweden

⁴Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden

⁵Department of Vascular Surgery, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden

Presenting Author: Jonathan Arvidsson

Synopsis

Motivation:

Goals:

Approach:

Results:

Full abstract & presentation

The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.

Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.

To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.

References

1. Ledermann HP, Schulte AC, Heidecker HG, et al. Blood oxygenation level-dependent magnetic resonance imaging of the skeletal muscle in patients with peripheral arterial occlusive disease. Circulation. 2006;113(25):2929-2935. doi:10.1161/CIRCULATIONAHA.105.605717 [doi]

2. Englund EK, Langham MC, Ratcliffe SJ, et al. Multiparametric assessment of vascular function in peripheral artery disease: dynamic measurement of skeletal muscle perfusion, blood-oxygen-level dependent signal, and venous oxygen saturation. Circ Cardiovasc Imaging. 2015;8(4):10.1161/CIRCIMAGING.114.002673 e002673. doi:10.1161/CIRCIMAGING.114.002673 [doi]

3. Jacobi B, Bongartz G, Partovi S, et al. Skeletal muscle BOLD MRI: from underlying physiological concepts to its usefulness in clinical conditions. J Magn Reson Imaging. 2012;35(6):1253-1265. doi:10.1002/jmri.23536 [doi]

4. Nordanstig J, Törngren K, Arvidsson J, Eriksson S, Falkenberg M, et al. (2022) A lower limb BOLD-MRI tissue perfusion protocol correlate to clinical disease stage, objective functional limitations, and health-related quality of life in patients with peripheral arterial occlusive disease. J Cardiovasc Med Cardiol 9(3): 028-29. DOI: 10.17352/2455-2976.000184 [doi]

5. Bakermans AJ, Wessel CH, Zheng KH, Groot PFC, Stroes ESG, Nederveen AJ. Dynamic magnetic resonance measurements of calf muscle oxygenation and energy metabolism in peripheral artery disease. J Magn Reson Imaging. 2020;51(1):98-107. doi:10.1002/jmri.26841 [doi]

6. Li Z, Muller MD, Wang J, et al. Dynamic characteristics of T2*-weighted signal in calf muscles of peripheral artery disease during low-intensity exercise. J Magn Reson Imaging. 2017;46(1):40-48. doi:10.1002/jmri.25532 [doi]

7. Törngren K, Eriksson S, Arvidsson J, Falkenberg M, Johnsson ÅA, Sjöberg C, Lagerstrand K, Nordanstig J. A Reperfusion BOLD-MRI Tissue Perfusion Protocol Reliably Differentiate Patients with Peripheral Arterial Occlusive Disease from Healthy Controls. Journal of Clinical Medicine. 2021; 10(16):3643. https://doi.org/10.3390/jcm101636438. [doi]

8. Arvidsson J, Eriksson S, Johansson E, Lagerstrand K. Arterial occlusion duration affects the cuff-induced hyperemic response in skeletal muscle BOLD perfusion imaging as shown in young healthy subjects. MAGMA. 2023;36(6):897-910. doi:10.1007/s10334-023-01105-y [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/305-04-010