669-01-003 ISMRM Abstract

Transient Nuclear Overhauser Effect (tNOE) MRI Detects Diffuse Lipid Related Pathology in Multiple Sclerosis

Primary: Neuro - Multiple Sclerosis

Secondary: Neuro - White Matter

669-01-003 · Neuroinflammation: Metabolites, Function, and AI · Thursday, 14 May, 8:30 AM–9:25 AM · Digital Posters Row J

Keywords: Multiple Sclerosis Magnetization transfer MRI White matter tracts Magnetization transfer (MT) Multiple Sclerosis brain

Accepted

Blake A Benyard ¹, Dushyant Kumar¹, Anshuman Swain¹, neil wilson¹, Sunil K Khokhar¹, Paul S Jacobs¹, Nikka Bakhtiar², Matthew Schindler², Mohammad Haris¹, Ravinder Reddy¹

¹Department of Radiology, Center for Advanced Metabolic Imaging in Precision Medicine (CAMIPM), University of Pennsylvania, Philadelphia, United States of America

²Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, United States of America

Presenting Author: Blake A Benyard

Synopsis

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References

1. C. Walton, R. King, L. Rechtman, W. Kaye, E. Leray, R.A. Marrie, N. Robertson, N. La Rocca, B. Uitdehaag, I. van der Mei, M. Wallin, A. Helme, C.A. Napier, N. Rijke, P. Baneke, Rising prevalence of multiple sclerosis worldwide: Insights from the Atlas of MS, third edition, Mult. Scler. J. 26 (2020) 1816 –1821.

2. L.M. Nelson, M.T. Wallin, R.A. Marrie, W.J. Culpepper, A. Langer-Gould, J. Campbell, S. Buka, H. Tremlett, G. Cutter, W. Kaye, L. Wagner, N.G. Larocca, A new way to estimate neurologic disease prevalence in the United States: Illustrated with MS, Neurology 92 (2019) 469–480.

3. Iannucci G, Rovaris M, Giacomotti L, Comi G, Filippi M. Correlation of multiple sclerosis measures derived from T2-weighted, T1-weighted, magnetization transfer, and diffusion tensor MR imaging. AJNR Am J Neuroradiol. 2001;22(8):1462-1467.

4. Kumar, D, Benyard, B, Soni, ND, et al. Feasibility of transient nuclear Overhauser effect imaging in brain at 7 T. Magn Reson Med. 2023; 89: 1357-1367

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/669-01-003