Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
463-04-005 ISMRM Abstract

Grayout signs seen in the brain after mild traumatic injury using divided subtracted inversion recovery sequences

Primary: Neuro - Gray Matter
Secondary: Neuro - Traumatic Brain Injury
463-04-005 · Advanced Microstructural Imaging of White Matter and Traumatic Brain Injury · Tuesday, 12 May, 2:35 PM–3:30 PM · Digital Posters Row D
Keywords: Acquisition Methods Contrast Mechanisms Grey matter MTBI Magnetization transfer (MT)
Accepted
Paul M Condron 1,2, Daniel Cornfeld1,2, Gil Newburn1, Maryam Tayebi1,3, Eryn Kwon1,3, Miriam Scadeng2, Mark Bydder1, Samantha Holdsworth1,2, Graeme M Bydder1,4
1Mātai Medical Research Institute, Gisborne, New Zealand
2University of Auckland, Auckland, New Zealand
3Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand
4University of California, San Diego, United States of America
Presenting Author: Paul M Condron

Synopsis

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References

1. 1. Newburn G, McGeown JP, Kwon EE et al (2023) Targeted MRI (tMRI) of small increases in the T1 of normal appearing white matter in mild traumatic brain injury (mTBI) using a divided subtracted inversion recovery (dSIR) sequence. OBM Neurobiology 7(4): doi: 10.21926/obm.neurobiol.2304201. [doi]
2. 2. Cornfeld DM, Newburn G, Condron P et al. Ultra-high contrast MRI: a new technique for recognizing secondary changes to the brain in patients with persistent symptoms following traumatic injury. Neuroradiology (in press).
3. 3. Newburn G, Condron P, Kwon EE et al (2024) Diagnosis of delayed post-hypoxic leukoencephalopathy (Grinker's myelinopathy) with MRI using divided subtracted inversion recovery (dSIR) sequences: time for reappraisal of the syndrome? Diagnostics 14(4):418. https://doi.org/10.3390/diagnostics14040418. [doi]
4. 4. Cornfeld DM, Condron P, Bydder M et al. Ultra-high contrast MRI of the brain and spinal cord using directly acquired and synthetic bipolar inversion recovery (BLAIR) images. Preprints 2025. doi:10.20944/preprints202505.2380.v6. [doi]
5. 5. Condron P, Cornfeld DM, Scadeng M et al ( 2024) Ultra-high contrast MRI: the whiteout sign shown with divided subtracted inversion recovery (dSIR) sequences in post-insult leukoencephalopathy syndromes (PILS). Tomography 10(7):983-1013
6. 6. Bydder M, Girard OM, Melzer TR, et al. The Role of Incidental Magnetization Transfer in Divided Subtracted Inversion Recovery. NMR Biomed. 2025;38(12):e70165. doi:10.1002/nbm.70165 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/463-04-005