Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
352-02-007 / 352-02-007 ISMRM Abstract

Towards reproducible perivascular space quantification: an open-source perivascular space segmentation benchmark

Primary: Neuro - Neurofluids
Secondary: Analysis Methods - Segmentation and Detection
352-02-007 · Segmentation: Automated, Scalable, and Clinically Oriented MRI Analysis · Monday, 11 May, 1:50 PM–3:26 PM · Power Pitch Theatre 2
352-02-007 · Segmentation: Automated, Scalable, and Clinically Oriented MRI Analysis · Monday, 11 May, 1:50 PM–3:26 PM · Power Pitch Theatre 2
Keywords: Segmentation Perivascular spaces Reproducibility Open Science Benchmark
Accepted
Merel M van der Thiel 1,2,3, Eva M van Heese4,5, Britt TJ van den Heuvel1, Jacobus F Jansen1,2,6, Brady J Williams7,8, Jose Bernal9,10,11
1Maastricht University Medical Center, Maastricht, Netherlands
2Mental Health and Neuroscience Research Institute, Maastricht University, Maastricht, Netherlands
3Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, United States of America
4Amsterdam Neuroscience, Amsterdam, Netherlands
5Department of Anatomy and Neurosciences, Amsterdam, Vrije Universiteit Amsterdam, Amsterdam, Netherlands
6Department of Electrical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands
7Pediatric Neuroimaging Research Consortium (PNRC), Cincinnati Children’s Hospital Medical Center, Cincinnati, United States of America
8Department of Psychology, University of Cincinnati, Cincinnati, United States of America
9Cerebrovascular Imaging and Research Lab, Department Artificial Intelligence in Biomedical Engineering (AIBE), Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany
10German Centre for Neurodegenerative Diseases (DZNE), Magdeburg, Germany
11Institute for Neuroscience and Cardiovascular Research, Row Fogo Centre for Research into Ageing and The Brain, Department of Neuroimaging Sciences, The University of Edinburgh, Edinburgh, United Kingdom
Presenting Author: Merel M van der Thiel

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References

1. Potter, Gillian M., Fergus N. Doubal, Caroline A. Jackson, Francesca M. Chappell, Cathie L. Sudlow, Martin S. Dennis, and Joanna M. Wardlaw. 2015. “Enlarged Perivascular Spaces and Cerebral Small Vessel Disease.” International Journal of Stroke: Official Journal of the International Stroke Society 10 (3): 376–81.
2. Wardlaw, Joanna M., Helene Benveniste, Maiken Nedergaard, Berislav V. Zlokovic, Humberto Mestre, Hedok Lee, Fergus N. Doubal, et al. 2020. “Perivascular Spaces in the Brain: Anatomy, Physiology and Pathology.” Nature Reviews. Neurology 16 (3): 137–53.
3. Waymont, Jennifer M. J., Maria Del C. Valdés Hernández, José Bernal, Roberto Duarte Coello, Rosalind Brown, Francesca M. Chappell, Lucia Ballerini, and Joanna M. Wardlaw. 2024. “Systematic Review and Meta-Analysis of Automated Methods for Quantifying Enlarged Perivascular Spaces in the Brain.” NeuroImage 297 (120685): 120685.
4. Yamamoto, Erin A., Jacob H. Bagley, Mathew Geltzeiler, Olabisi R. Sanusi, Aclan Dogan, Jesse J. Liu, and Juan Piantino. 2024. “The Perivascular Space Is a Conduit for Cerebrospinal Fluid Flow in Humans: A Proof-of-Principle Report.” Proceedings of the National Academy of Sciences of the United States of America 121 (42): e2407246121.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/352-02-007