Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
501-04-006 ISMRM Abstract

Accuracy, Repeatability, and Reproducibility of Free-Breathing Liver Fat Quantification at 0.55 T, 1.5 T, and 3 T

Primary: Body - Liver
Secondary: Physics & Engineering - Low-Field MRI
501-04-006 · Applications of Quantitative MRI in the Body · Wednesday, 13 May, 4:00 PM–5:50 PM · Hall 1A
Keywords: Fat and Fat/Water Separation Liver Proton density fat fraction (PDFF) Free-Breathing 0.55T
Accepted
Shu-Fu Shih 1, Fei Han2, Brian P Toner3, Xiaodong Zhong1,4, Maria Altbach5,6, Ali Bilgin5,6,7, Vibhas Deshpande8, Waqas Majeed9, David S Lu1, Holden H Wu1,4
1David Geffen School of Medicine, University of California Los Angeles, Los Angeles, United States of America
2Siemens Medical Solutions, Los Angeles, United States of America
3Applied Mathematics, University of Arizona, Tucson, United States of America
4Department of Bioengineering, University of California Los Angeles, Los Angeles, United States of America
5Radiology and Imaging Science, University of Arizona, Tucson, United States of America
6Biomedical Engineering, University of Arizona, Tucson, United States of America
7Electrical and Computer Engineering, University of Arizona, Tucson, United States of America
8Siemens Medical Solutions, Austin, United States of America
9MR R&D Collaborations, Siemens Medical Solutions USA, Inc., Chicago, United States of America
Presenting Author: Shu-Fu Shih

Synopsis

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References

1. QIBA Proton Density Fat Fraction Biomarker Committee. MRI-Based Proton Density Fat Fraction (PDFF) of the Liver Quantitative Imaging Biomarkers Alliance Profile Stage: Consensus Maintenance version June 19, 2024.
2. Gu J, Liu S, Du S, Zhang Q, Xiao J, Dong Q, Xin Y. Diagnostic value of MRI-PDFF for hepatic steatosis in patients with non-alcoholic fatty liver disease: a meta-analysis. European Radiology 2019;29(7):3564-3573. doi: 10.1007/s00330-019-06072-4. [doi]
3. Azizi N, Naghibi H, Shakiba M, Morsali M, Zarei D, Abbastabar H, Ghanaati H. Evaluation of MRI proton density fat fraction in hepatic steatosis: a systematic review and meta-analysis. European Radiology 2025;35(4):1794-1807. doi: 10.1007/s00330-024-11001-1. [doi]
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14. Shih SF, Kafali SG, Calkins KL, Wu HH. Uncertainty‐aware physics‐driven deep learning network for free‐breathing liver fat and R2* quantification using self‐gated stack‐of‐radial MRI. Magnetic Resonance in Medicine 2023;89(4):1567-1585. doi: 10.1002/mrm.29525. [doi]
15. Zhong X, Nickel MD, Kannengiesser SA, Dale BM, Han F, Gao C, Shih SF, Dai Q, Curiel O, Tsao TC. Accelerated free‐breathing liver fat and R2* quantification using multi‐echo stack‐of‐radial MRI with motion‐resolved multidimensional regularized reconstruction: Initial retrospective evaluation. Magnetic Resonance in Medicine 2024;92(3):1149-1161. doi: 10.1002/mrm.30117. [doi]
16. Fu Z, Johnson K, Altbach MI, Bilgin A. Cancellation of streak artifacts in radial abdominal imaging using interference null space projection. Magnetic Resonance in Medicine 2022;88(3):1355-1369. doi: 10.1002/mrm.29285. [doi]
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http://echo.ismrm.org/p/ISMRM2026/501-04-006