369-02-006 ISMRM Abstract

Detecting Neuromelanin Contrast in Substantia Nigra and Locus Coeruleus Utilizing Amplitude Maps of MRV: A Preliminary Study

Primary: Contrast Mechanisms - Multi-Contrast

Secondary: Neuro - Parkinson's Disease

369-02-006 · Imaging Parkinson’s Disease: Multimodal Biomarkers of Progression and Phenotype · Monday, 11 May, 9:15 AM–10:10 AM · Digital Posters Row J

Keywords: Substantia Nigra Locus Coeruleus Magnetic Resonance Venography NEUROMELANIN CONTRAST Neuromelanin-Sensitive Magnetic Resonance Imaging

Accepted

Cuili Kuang ¹, Liang Li¹, Wenbing Yang¹, Changsheng Liu¹, Yunfei Zha¹

¹Department of Radiology, Renmin Hospital of Wuhan University, Wuhan, China

Presenting Author: Cuili Kuang

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References

1. Sasaki M, Shibata E, Tohyama K, Takahashi J, Otsuka K, Tsuchiya K, et al. Neuromelanin magnetic resonance imaging of locus ceruleus and substantia nigra in Parkinson's disease. Neuroreport 2006; 17(11):1215-8. DOI: 10.1097/01.wnr.0000227984.84927.a7. PMID: 16837857. [doi] [pmid]

2. Langley J, Huddleston DE, Chen X, Sedlacik J, Zachariah N, Hu X. A multicontrast approach for comprehensive imaging of substantia nigra. Neuroimage 2015;112:7-13. DOI: 10.1016/j.neuroimage.2015.02.045. PMID: 25731994. [doi] [pmid]

3. Trujillo P, Summers PE, Ferrari E, Zucca FA, Sturini M, Mainardi LT, et al. Contrast mechanisms associated with neuromelanin-MRI. Magnetic resonance in medicine 2017; 78(5):1790-800. DOI: 10.1002/mrm.26584. PMID: 28019018. [doi] [pmid]

4. Brown RW, Cheng YN, Haacke EM, Thompson MR, Venkatesan R. Magnetic Resonance Imaging: Physical Principles and Sequence Design. Wiley-Liss, New York 2014. DOI:10.1002/9781118633953. [doi]

5. Vitali P, Pan MI, Palesi F, Germani G, Faggioli A, Anzalone N, et al. Substantia Nigra Volumetry with 3-T MRI in De Novo and Advanced Parkinson Disease. Radiology 2020; 296(2):401-10. DOI: 10.1148/radiol.2020191235. PMID: 32544035. [doi] [pmid]

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http://echo.ismrm.org/p/ISMRM2026/369-02-006