Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
466-06-003 ISMRM Abstract

Enabling Lower Dose Contrast Enhanced Cardiac Magnetic Resonance Imaging at Mid-Field (0.55T) with Gadopiclenol

Accepted
Katherine Binzel1, Juliet Varghese 2, Matthew Tong3,4, Yuchi Han4, Orlando Simonetti2,3,4,5
1Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, United States of America
2Department of Radiology, The Ohio State University, Columbus, United States of America
3The Ohio State University, Columbus, United States of America
4The Ohio State University Wexner Medical Center, Columbus, United States of America
5Department of Radiology, The Ohio State University Wexner Medical Center, Columbus, United States of America
Presenting Author: Juliet Varghese

Synopsis

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References

1. Helali J, Ramesh K, Brown J, et al. Late Gadolinium Enhancement on Cardiac MRI: A Systematic Review and Meta-analysis of Prognosis Across Cardiomyopathies. Int J Cardiol. 2025 Jan 15;419:132711. DOI: 10.1016/j.ijcard.2024.132711. [doi]
2. Meier, C, Eisenblätter, M, Gielen, S. Myocardial Late Gadolinium Enhancement (LGE) in Cardiac Magnetic Resonance Imaging (CMR)—An Important Risk Marker for Cardiac Disease. J. Cardiovasc. Dev. Dis. 2024, 11, 40. DOI: 10.3390/jcdd11020040. [doi]
3. Eichstaedt HW, Felix R, Danne O, et al. Imaging of Acute Myocardial Infarction by Magnetic Resonance Tomography (MRT) Using the Paramagnetic Relaxation Substance Gadolinium-DTPA. Cardiovasc Drugs Ther. 1989 Oct;3(5):779-88. DOI: 10.1007/BF01857631. [doi]
4. Grobner T. Gadolinium—A Specific Trigger for the Development of Nephrogenic Fibrosing Dermopathy and Nephrogenic Systemic Fibrosis? Nephrol Dial Transplant. 2006;21:1104–1108. DOI: 10.1093/ndt/gfl294. [doi]
5. Hao J, Pitrou C, Bourrinet P. A Comprehensive Overview of the Efficacy and Safety of Gadopiclenol: A New Contrast Agent for MRI of the CNS and Body. Invest Radiol. 2024 Feb 1;59(2):124-130. DOI: 10.1097/RLI.0000000000001025. [doi]
6. Robic C, Port M, Rousseaux O, et al. Physicochemical and Pharmacokinetic Profiles of Gadopiclenol: A New Macrocyclic Gadolinium Chelate with High T1 Relaxivity. Invest Radiol. 2019;54:475–484. DOI: 10.1097/RLI.0000000000000563. [doi]
7. Heidenreich JF, Chu SY, Grunz JP, et al. Gadopiclenol Enables Reduced Gadolinium Dose While Maintaining Quality of Pulmonary Arterial Enhancement for Pulmonary MRA: An Opportunity for Improved Safety and Sustainability. Invest Radiol. 2025 Jan 24. DOI: 10.1097/RLI.0000000000001154. [doi]
8. Vasanawala S. Clinical Applications of Gadopiclenol in Pediatric MRI. Supplement to Applied Radiology. 2024;(2).
9. Kaushal A, Crawley R, Jeljeli S, et al. Use of a 0.55T 80cm-wide Bore Scanner for Cardiac Imaging in Bariatric and Claustrophobic Patients: A Preliminary Single Centre Experience. J. Cardiovasc. Magn. Reson., 2024, 101017. DOI: 10.1016/j.jocmr.2024.101017. [doi]

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