Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
563-02-002 ISMRM Abstract

Longitudinal quantitative MRI of cartilage degeneration in ACL-reconstructed patients using ultrashort echo time adiabatic T1

Accepted
Dina Moazamian1, Jiayang Wu1,2, Mohamad Amin Cheraghi1, Hamidreza Shaterian Mohammadi1, Bhavsimran Malhi3, Jiyo S Athertya1, Mahyar Daskareh1, Yajun Ma1, Susan Bukata1, Eric Y Chang1,4, Saeed Jerban1, Christine B Chung1, Jiang Du1,4
1University of California, Berkeley, United States of America
2Medical Imaging Center, The First Affiliated Hospital of Jinan University, Guangzhou, China
3Department of Radiology, Trinity Health Mid Atlantic/Mercy Catholic Medical Center, Darby, United States of America
4Radiology Service, VA San Diego Healthcare System, La Jolla, California, San Diego, United States of America
Presenting Author: Soo Hyun Shin

Synopsis

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References

1. Rodriguez-Merchan EC, Encinas-Ullan CA. Knee Osteoarthritis Following Anterior Cruciate Ligament Reconstruction: Frequency, Contributory Elements, and Recent Interventions to Modify the Route of Degeneration. Arch Bone Jt Surg. 2022;10(11):951-958. doi:10.22038/ABJS.2021.52790.2616 [doi]
2. Toguchi K, Watanabe A, Horii M, et al. Longitudinal Analysis of Knee Articular Cartilage Degeneration After Anterior Cruciate Ligament Reconstruction: Comparison of T1rho and T2 Mapping. Cartilage. 2024;16(2):125-138. doi:10.1177/19476035241264013 [doi]
3. Li X, Kuo D, Theologis A, et al. Cartilage in Anterior Cruciate Ligament–Reconstructed Knees: MR Imaging T1ρ and T2—Initial Experience with 1-year Follow-up. Radiology. 2011;258(2):505-514. doi:10.1148/radiol.10101006 [doi]
4. Chang EY, Ma Y, Du J. MR Parametric Mapping as a Biomarker of Early Joint Degeneration. Sports Health. 2016;8(5):405-411. doi:10.1177/1941738116661975 [doi]
5. Duvvuri U, Reddy R, Patel SD, Kaufman JH, Kneeland JB, Leigh JS. T1ρ-relaxation in articular cartilage: Effects of enzymatic degradation. Magn Reson Med. 1997;38(6):863-867. doi:10.1002/mrm.1910380602 [doi]
6. Jerban S, Ma Y, Kasibhatla A, et al. Ultrashort echo time adiabatic T1ρ (UTE-Adiab-T1ρ) is sensitive to human cadaveric knee joint deformation induced by mechanical loading and unloading. Magn Reson Imaging. 2021;80:98-105. doi:10.1016/j.mri.2021.04.014 [doi]
7. Ma YJ, Carl M, Searleman A, Lu X, Chang EY, Du J. Three Dimensional Adiabatic T1ρ Prepared Ultrashort Echo Time Cones (3D AdiabT1ρ UTE-Cones) Sequence for Whole Knee Imaging. Magn Reson Med. 2018;80(4):1429-1439. doi:10.1002/mrm.27131 [doi]
8. H S, C P, S L, et al. Magic angle effect plays a major role in both T1rho and T2 relaxation in articular cartilage. PubMed. Accessed October 9, 2025. https://pubmed.ncbi.nlm.nih.gov/28161394/ [pmid]

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