Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
364-02-013 ISMRM Abstract

Self-Supervised Deep Learning for Label-Free Brain Metastasis Detection in Clinical MR Imaging

Accepted
Anne Rückert 1, Oscar van der Heide1, Mark Savenije1, Jelmer van Lune1, Niels C.P.J Raaijmakers2, Marielle Philippens2, Enrica Seravalli2, Mischa de Ridder2, Cornelis A van den Berg1
1Computational Imaging Group for MRI Therapy & Diagnostics, Department of Radiotherapy, UMC Utrecht, Utrecht, Netherlands
2Department of Radiotherapy, UMC Utrecht, Utrecht, Netherlands
Presenting Author: Anne Rückert

Synopsis

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References

1. Takei H, Rouah E, Ishida Y. Brain metastasis: clinical characteristics, pathological findings and molecular subtyping for therapeutic implications. Brain Tumor Pathol 33, 1–12 (2016). https://doi.org/10.1007/s10014-015-0235-3. [doi]
2. Pekmezci M, Perry A. Neuropathology of brain metastases. Surg Neurol Int. 2013 May 2;4(Suppl 4):S245-55. PMID: 23717796; PMCID: PMC3656562. [pmid]
3. Grøvik E, Yi D, Iv M, Tong E, Rubin D, Zaharchuk G. Deep learning enables automatic detection and segmentation of brain metastases on multisequence MRI. J Magn Reson Imaging. 2020 Jan;51(1):175-182. doi: 10.1002/jmri.26766. [doi]
4. Dikici E, Ryu JL, Demirer M, Bigelow M, White RD, Slone W, Erdal BS, Prevedello LM. Automated Brain Metastases Detection Framework for T1-Weighted Contrast-Enhanced 3D MRI. IEEE J Biomed Health Inform. 2020 Oct;24(10):2883-2893. doi: 10.1109/JBHI.2020.2982103. [doi]
5. Ozkara BB, Chen MM, Federau C, Karabacak M, Briere TM, Li J, Wintermark M. Deep Learning for Detecting Brain Metastases on MRI: A Systematic Review and Meta-Analysis. Cancers (Basel). 2023 Jan 4;15(2):334. doi: 10.3390/cancers15020334. [doi]
6. Baugh M, Tan J, Müller JP, Dombrowski M, Batten J, Kainz B. (2023). Many Tasks Make Light Work: Learning to Localise Medical Anomalies from Multiple Synthetic Tasks. In: Greenspan, H., et al. Medical Image Computing and Computer Assisted Intervention – MICCAI 2023. MICCAI 2023. Lecture Notes in Computer Science, vol 14220. Springer, Cham. https://doi.org/10.1007/978-3-031-43907-0_16. [doi]
7. Human Connectome Project (HCP) Young Adult Study. https://www.humanconnectome.org/study/hcp-young-adult. Accessed October 29, 2025.

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