Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
366-01-003 ISMRM Abstract

Subregional Cerebral Blood Flow Alterations and Their Cognitive Relevance in Cerebral Small Vessel Disease: Insights from ASL

Primary: Neuro - Stroke and Cerebrovascular Disorders
Secondary: Contrast Mechanisms - Arterial Spin Labelling
366-01-003 · Cerebral Small Vessel Disease: Imaging Biomarkers, Pathophysiology, and Clinical Impact · Monday, 11 May, 8:20 AM–9:15 AM · Digital Posters Row G
Keywords: Cognitive impairment Cerebral blood flow (CBF) Cerebral Small Vessel Disease (CSVD) Arterial Spin Labeling (ASL) Subcortical Gray Matter
Accepted
Xianqi Chen 1, Chen Li2, Yingjie Wang1, Shurong Wu3, Boyao Chen2, Xinxin Huo1,2, Jiaxiang xin4,5,6,7, Meng Li8, Lingfei Guo2, Changhu Liang2
1Department of Radiograpy, Shandong Provincial Hospital Affiliated to Shandong First Medical University (Shandong Provincial Hospital), Jinan, China
2Shandong Provincial Hospital Affiliated to Shandong First Medical University (Shandong Provincial Hospital), Jinan, China
3Binzhou Medical University, Yantai City, Shandong Province, China
4MR Collaborations, Siemens Healthineers Ltd., Shanghai, China
5Magnetic Resonance Research Collaboration, Siemens Healthineers Ltd, Shanghai, China
6Magnetic Resonance Research Collaboration, Shanghai, China
7MR Research Collaboration Team, Shanghai, China
8Jena University Hospital, Jena, Germany
Presenting Author: Xianqi Chen

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References

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8. Gyanwali B, Tan BYQ, Petr J, et al. Arterial Spin-Labeling Parameters and Their Associations with Risk Factors, Cerebral Small-Vessel Disease, and Etiologic Subtypes of Cognitive Impairment and Dementia. AJNR Am J Neuroradiol. 2022;43(10):1418–1427. DOI: 10.3174/ajnr.A7630. [doi]
9. Boot E M, van Leijsen E M C, Bergkamp M I, Tuladhar A M, de Leeuw F E. Structural network efficiency predicts cognitive decline in cerebral small vessel disease. NeuroImage: Clinical. 2020; 27: 102325. DOI: 10.1016/j.nicl.2020.102325. [doi]
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11. Ruan J, Jiaerken Y, Liu W, et al. Altered neurovascular coupling in patients with vascular cognitive impairment: a combined ASL-fMRI analysis. Front Aging Neurosci. 2023;15:1224525. DOI:10.3389/fnagi.2023.1224525. [doi]
12. Li Q, Yang Y, Reis C, et al. Cerebral small vessel disease. Cell Transplant. 2018;27(12):1711-1722. DOI:10.1177/0963689718795148. [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/366-01-003