Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
565-02-006 ISMRM Abstract

The Utility of Sodium Inversion Recovery MR Imaging to Identify Astrocytoma, IDH-mutant

Primary: Neuro - Tumors
Secondary: Neuro - White Matter
565-02-006 · Neuro-Oncology and Ear, Nose, and Throat Cancer · Wednesday, 13 May, 9:15 AM–10:10 AM · Digital Posters Row F
Keywords: Glioma Brain tumor 23Na MRI 3T MRI
Accepted
Koji Yamashita 1, Makoto Obara2, Kazufumi Kikuchi3, Daichi Momosaka3, Masaoki Kusunoki3, Yasutomo Katsumata2, Marc Van Cauteren2, Kousei Ishigami3
1Department of Molecular Imaging & Diagnosis, Kyushu University, Fukuoka, Japan
2Philips Japan, Tokyo, Japan
3Department of Clinical Radiology, Kyushu University, Fukuoka, Japan
Presenting Author: Koji Yamashita

Synopsis

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References

1. 1. Parsons DW, Jones S, Zhang X, et al. An integrated genomic analysis of human glioblastoma multiforme. Science. 2008; 321:1807-1812. PMID: 18772396 [pmid]
2. 2. Patel SH, Poisson LM, Brat DJ, et al. T2-FLAIR Mismatch, an Imaging Biomarker for IDH and 1p/19q Status in Lower-grade Gliomas: A TCGA/TCIA Project. Clin Cancer Res. 2017; 23:6078-6085. PMID: 28751449 [pmid]
3. 3. Jain R, Johnson DR, Patel SH, et al. "Real world" use of a highly reliable imaging sign: "T2-FLAIR mismatch" for identification of IDH mutant astrocytomas. Neuro Oncol. 2020; 22:936-943. PMID: 32064507 [pmid]
4. 4. Kinoshita M, Arita H, Takahashi M, et al. Impact of Inversion Time for FLAIR Acquisition on the T2-FLAIR Mismatch Detectability for IDH-Mutant, Non-CODEL Astrocytomas. Front Oncol. 2021; 10:596448. PMID: 33520709 [pmid]
5. 5. Park SI, Suh CH, Guenette JP, et al. The T2-FLAIR mismatch sign as a predictor of IDH-mutant, 1p/19q-noncodeleted lower-grade gliomas: a systematic review and diagnostic meta-analysis. Eur Radiol. 2021; 31:5289-5299. PMID: 33409784 [pmid]
6. 6. Gast LV, Platt T, Nagel AM, Gerhalter T. Recent technical developments and clinical research applications of sodium (23Na) MRI. Prog Nucl Magn Reson Spectrosc. 2023; 138-139:1-51. PMID: 38065665 [pmid]
7. 7. Nagel AM, Bock M, Hartmann C, et al. The potential of relaxation-weighted sodium magnetic resonance imaging as demonstrated on brain tumors. Invest Radiol. 2011; 46:539-547. PMID: 21577129 [pmid]
8. 8. Deguchi S, Oishi T, Mitsuya K, et al. Clinicopathological analysis of T2-FLAIR mismatch sign in lower-grade gliomas. Sci Rep. 2020; 10:10113. PMID: 32572107 [pmid]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/565-02-006