Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
352-03-008 / 352-03-008 ISMRM Abstract

FPR-pCASL for assessing cerebral microvascular pulsatility: technique optimization and validation

Primary: Neuro - Neurofluids
Secondary: Neuro - Blood Vessels
352-03-008 · Neurofluid Dynamics in Sleep and Disease · Monday, 11 May, 4:10 PM–5:46 PM · Power Pitch Theatre 2
352-03-008 · Neurofluid Dynamics in Sleep and Disease · Monday, 11 May, 4:10 PM–5:46 PM · Power Pitch Theatre 2
Keywords: Validation Optimization Glymphatic Function Pulsatility Microvascular networks
Accepted
Tianrui Zhao1,2, Jianing Tang1,2, Yining He1,2, Lirong Yan 1,2
1Biomedical Engineering, Northwestern University, Chicago, United States of America
2Radiology, Northwestern University, Chicago, United States of America
Presenting Author: Lirong Yan

Synopsis

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References

1. Schroth G, Klose U. Cerebrospinal fluid flow. I. Physiology of cardiac-related pulsation. Neuroradiology 1992;35(1):1-9.doi: 10.1007/BF00588270. [doi]
2. Iliff JJ, Wang M, Zeppenfeld DM, Venkataraman A, Plog BA, Liao Y, Deane R, Nedergaard M. Cerebral arterial pulsation drives paravascular CSF-interstitial fluid exchange in the murine brain. J Neurosci 2013;33(46):18190-18199.doi: 10.1523/JNEUROSCI.1592-13.2013. [doi]
3. de Riva N, Budohoski KP, Smielewski P, Kasprowicz M, Zweifel C, Steiner LA, Reinhard M, Fabregas N, Pickard JD, Czosnyka M. Transcranial Doppler pulsatility index: what it is and what it isn't. Neurocrit Care 2012;17(1):58-66. doi: 10.1007/s12028-012-9672-6. [doi]
4. Holmgren M, Wahlin A, Dunas T, Malm J, Eklund A. Assessment of Cerebral Blood Flow Pulsatility and Cerebral Arterial Compliance With 4D Flow MRI. J Magn Reson Imaging 2020;51(5):1516-1525. doi: 10.1002/jmri.26978. [doi]
5. Zhao T, Tang J, He Y, Gill NP, Gamez MT, Yan L. Assessing cerebral microvascular pulsatility using flow pulsatile‐resolved pseudo‐continuous arterial spin labeling MRI. Magnetic resonance in medicine. 2025 Jul 22. doi: 10.1002/mrm.70004. [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/352-03-008