Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
362-05-005 ISMRM Abstract

Neurochemical and Transcriptomic Bases of Cortical Network Vulnerability in Parkinson’s Disease with Probable RBD

Primary: Neuro - Parkinson's Disease
Secondary: Analysis Methods - Data Processing
362-05-005 · Spectroscopy and Spectroscopic Imaging: Neuro II · Monday, 11 May, 4:10 PM–5:05 PM · Digital Posters Row C
Keywords: Parkinson's Disease Morphometric INverse Divergence (MIND) REM sleep behavior disorder Neurotransmitter receptor mapping Imaging transcriptomic association
Accepted
Pengfei Zhang 1,2, Kuanrong Jian1,2, Xinyue Wan1,2, Qiyong Gong1,2,3,4
1Huaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital of Sichuan University, Chengdu, China
2Psychoradiology Key Laboratory of Sichuan Province, West China Hospital of Sichuan University, Chengdu, China
3Research Unit of Psychoradiology, Chinese Academy of Medical Sciences, Chengdu, China
4Department of Radiology, West China Xiamen Hospital of Sichuan University, Xiamen, China
Presenting Author: Pengfei Zhang

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References

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4. Pardo J, Montal V, Campabadal A et al (2024) Cortical Macro- and Microstructural Changes in Parkinson's Disease with Probable Rapid Eye Movement Sleep Behavior Disorder. Mov Disord 39:814–824. doi:10.1002/mds.29761 [doi]
5. Yan S, Lu J, Duan B et al (2024) Quantitative susceptibility mapping of multiple system atrophy and Parkinson's disease correlates with neurotransmitter reference maps. Neurobiol Dis 198:106549. doi:10.1016/j.nbd.2024.106549 [doi]
6. Dan X J, Wang Y W, Sun J Y et al (2024) Reorganization of intrinsic functional connectivity in early-stage Parkinson's disease patients with probable REM sleep behavior disorder. NPJ Parkinsons Dis 10:5. doi:10.1038/s41531-023-00617-7 [doi]
7. Wang Y, Xiao Y, Xing Y et al (2024) Morphometric similarity differences in drug-naive Parkinson's disease correlate with transcriptomic signatures. CNS Neurosci Ther 30:e14680. doi:10.1111/cns.14680 [doi]
8. Rahayel S, Tremblay C, Vo A et al (2023) Mitochondrial function-associated genes underlie cortical atrophy in prodromal synucleinopathies. Brain 146:3301–3318. doi:10.1093/brain/awad044 [doi]

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http://echo.ismrm.org/p/ISMRM2026/362-05-005