Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
431-03-013 / 431-03-013 ISMRM Abstract

Joint Image Reconstruction and T1 Fitting for Multi-Dose Contrast-Enhanced Multitasking MRI

Primary: Acquisition & Reconstruction - Quantitative Imaging: relaxometry, multi-parametric, MR Fingerprinting, and synthetic MRI
Secondary: Cardiovascular - Myocardium
431-03-013 · Image Reconstruction · Tuesday, 12 May, 4:00 PM–5:36 PM · Roof Terrace
431-03-013 · Image Reconstruction · Tuesday, 12 May, 4:00 PM–5:36 PM · Roof Terrace
Keywords: Image Reconstruction Cardiac MRI Ferumoxytol-enhanced imaging Fractional myocardial blood volume T1-Weighted Contrast-Enhanced MRI
Accepted
Anqi Liu1,2, Xi Chen 1, Thomas Coudert1,3, Kim-Lien Nguyen1,2,3,4, Anthony G Christodoulou1,2,4
1Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, United States of America
2Department of Bioengineering, University of California Los Angeles, Los Angeles, United States of America
3Division of Cardiology, David Geffen School of Medicine at UCLA and VA Greater Los Angeles Healthcare System, Los Angeles, United States of America
4Physics and Biology in Medicine Graduate Program, University of California Los Angeles, Los Angeles, United States of America
Presenting Author: Xi Chen

Synopsis

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References

1. Ugander M, Oki AJ, Hsu LY, Kellman P, Greiser A, Aletras AH, Sibley CT, Chen MY, Bandettini WP, Arai AE. Extracellular volume imaging by magnetic resonance imaging provides insights into overt and sub-clinical myocardial pathology. Eur Heart J. 2012 May;33(10):1268-78. doi: 10.1093/eurheartj/ehr481. Epub 2012 Jan 24. PMID: 22279111; PMCID: PMC3350985. [doi] [pmid]
2. Colbert CM, Thomas MA, Yan R, Radjenovic A, Finn JP, Hu P, Nguyen KL. Estimation of fractional myocardial blood volume and water exchange using ferumoxytol-enhanced magnetic resonance imaging. J Magn Reson Imaging. 2021 Jun;53(6):1699-1709. doi: 10.1002/jmri.27494. Epub 2020 Dec 31. PMID: 33382176; PMCID: PMC8297410. [doi] [pmid]
3. Christodoulou AG, Shaw JL, Nguyen C, Yang Q, Xie Y, Wang N, Li D. Magnetic resonance multitasking for motion-resolved quantitative cardiovascular imaging. Nat Biomed Eng. 2018 Apr;2(4):215-226. doi: 10.1038/s41551-018-0217-y. Epub 2018 Apr 9. PMID: 30237910; PMCID: PMC6141200. [doi] [pmid]
4. Robinson, A, Chow, K, Salerno, M. Myocardial T1 and ECV Measurement: Underlying Concepts and Technical Considerations. J Am Coll Cardiol Img. 2019 Nov, 12 (11_Part_2) 2332–2344. https://doi.org/10.1016/j.jcmg.2019.06.031 [doi]
5. Colbert CM, Le AH, Shao J, Currier JW, Ajijola OA, Hu P, Nguyen KL. Ferumoxytol-enhanced magnetic resonance T1 reactivity for depiction of myocardial hypoperfusion. NMR Biomed. 2021 Jul;34(7):e4518. doi: 10.1002/nbm.4518. Epub 2021 Apr 8. PMID: 33830561; PMCID: PMC8287706. [doi] [pmid]
6. Serry FM, Ma S, Mao X, Han F, Xie Y, Han H, Li D, Christodoulou AG. Dual flip-angle IR-FLASH with spin history mapping for B1+ corrected T1 mapping: Application to T1 cardiovascular magnetic resonance multitasking. Magn Reson Med. 2021 Dec;86(6):3182-3191. doi: 10.1002/mrm.28935. Epub 2021 Jul 26. PMID: 34309072; PMCID: PMC8568626. [doi] [pmid]

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http://echo.ismrm.org/p/ISMRM2026/431-03-013