Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
562-06-014 Registered Abstract

Comparing the performance of qBOLD models to quantify oxygen extraction fraction using Monte Carlo over mice angiograms

Primary: Contrast Mechanisms - Oxygenation
Secondary: Brain Function and fMRI - fMRI Analysis
562-06-014 · fMRI: Preclinical · Wednesday, 13 May, 4:55 PM–5:50 PM · Digital Posters Row C
Keywords: Oxygen extraction fraction Quantitative BOLD MRI simulation Two-photon microscopy
Accepted
Alexis Cinq-Mars1, Ghislain Tedondje1, Aurelie Beaudoin1, Michèle Desjardins1,2, Louis Gagnon 3
1Physics, Engineering Physics and Optics, Université Laval, Québec, Canada
2Medical Physics, CHU de Québec - Université Laval, Québec, Canada
3Radiology and Nuclear Medicine, Université Laval, Québec, Canada
Presenting Author: Louis Gagnon

Synopsis

Motivation:
Goals:
Approach:
Hypothesis:
Full abstract & presentation

The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.

Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.

To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.

Log in

References

1. Jian Z, Wang X, Tian M, et al. Review of the Research Progress of Human Brain Oxygen Extraction Fraction by Magnetic Resonance Imaging. Oxidative Med Cell Longev. 2022;2022(1):4554271. doi:10.1155/2022/4554271 [doi]
2. Valable S, Corroyer-Dulmont A, Chakhoyan A, et al. Imaging of brain oxygenation with magnetic resonance imaging: A validation with positron emission tomography in the healthy and tumoural brain. J Cereb Blood Flow Metab. 2016;37(7):2584-2597. doi:10.1177/0271678x16671965 [doi]
3. He X, Yablonskiy DA. Quantitative BOLD: Mapping of human cerebral deoxygenated blood volume and oxygen extraction fraction: Default state. Magn Reson Med. 2007;57(1):115-126. doi:10.1002/mrm.21108 [doi]
4. Le LNN, Wheeler GJ, Holy EN, et al. Cortical oxygen extraction fraction using quantitative BOLD MRI and cerebral blood flow during vasodilation. Front Physiol. 2023;14:1231793. doi:10.3389/fphys.2023.1231793 [doi]
5. Ulrich X, Yablonskiy DA. Separation of cellular and BOLD contributions to T2* signal relaxation. Magn Reson Med. 2016;75(2):606-615. doi:10.1002/mrm.25610 [doi]
6. Cho J, Kee Y, Spincemaille P, et al. Cerebral metabolic rate of oxygen (CMRO2) mapping by combining quantitative susceptibility mapping (QSM) and quantitative blood oxygenation level‐dependent imaging (qBOLD). Magn Reson Med. 2018;80(4):1595-1604. doi:10.1002/mrm.27135 [doi]
7. Cho J, Lee J, An H, Goyal MS, Su Y, Wang Y. Cerebral oxygen extraction fraction (OEF): Comparison of challenge-free gradient echo QSM+qBOLD (QQ) with 15O PET in healthy adults. J Cereb Blood Flow Metab. 2020;41(7):1658-1668. doi:10.1177/0271678x20973951 [doi]
8. Boyer Q, Lee D, Cho H, Cho J. QQ-based oxygen extraction fraction (OEF) mapping in mouse brain: Initial Experience. ISMRM Annu Meet. Published online 2025. doi:10.58530/2025/3646 [doi]
9. Charest J, Walsh M, Genois É, et al. Comparison of compartmental analytical Blood‐Oxygen‐Level‐Dependent functional Magnetic Resonance Imaging models against Monte Carlo simulations performed over cortical micro‐angiograms. NMR Biomed. Published online 2024:e5252. doi:10.1002/nbm.5252 [doi]
10. Cho, J., Lee, D., Boyer, Q., et al. “QQ-based oxygen extraction fraction (OEF) mapping in mouse brain: Initial Experience.” Presented at the ISMRM (International Society for Magnetic Resonance in Medicine) 2025 Annual Meeting; Paper ID: 3646.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/562-06-014