Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
407-04-006 ISMRM Abstract

Semiquantitative MRI scores and CNR correlate with bone quality (histology and micro-CT) after osteochondral implantation

Primary: Musculoskeletal - Bone
Secondary: Preclinical Animal & in vitro MR - Large Animals, Nonhuman Primates
407-04-006 · New Outcome Measures for Studying the Joint · Tuesday, 12 May, 4:00 PM–5:50 PM · Meeting Room 1.40
Keywords: Preclinical Tissue Characterization Biomarkers Bone Cartilage
Accepted
Felix Merlin König 1, Veronika Janacova2, Markus Schreiner3, Marlene Stuempflen1, Vladimir Juras2, Pavol Szomolanyi2,4, Janina Patsch1, Giuseppe Filardo5, Ali Guermazi6, Siegfried Trattnig1,7,8,9
1Medical University of Vienna, Vienna, Austria
2Department of Biomedical Imaging and Image-guided Therapy, High Field MR Centre, Medical University of Vienna, Vienna, Austria
3Department of Orthopedics and Trauma-Surgery, Medical University of Vienna, Vienna, Austria
4Department of Imaging Methods, Institute of Measurement Science, Slovak Academy of Sciences, Bratislava, Slovakia
5Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland
6Boston University, Boston, United States of America
7Christian Doppler Laboratory for MR Imaging Biomarkers, Vienna, Austria
8Institute for Clinical Molecular MRI, Karl Landsteiner Society, St. Pölten, Austria
9Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria
Presenting Author: Felix Merlin König

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References

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2. Long SS, Yablon CM, Eisenberg RL. Bone marrow signal alteration in the spine and sacrum. Am J Roentgenol. 2010;195:. doi:10.2214/ajr.09.4134 [doi]
3. Meric G, Gracitelli GC, McCauley JC, Pulido PA, Chang EY, Chung CB, et al. Osteochondral Allograft MRI Scoring System (OCAMRISS) in the knee: interobserver agreement and clinical application. Cartilage. 2015;6:142-149. doi:10.1177/1947603515573987 [doi]
4. Chang HK, Hsu TW, Ku J, Wu JC, Lirng JF, et al. Simple parameters of synthetic MRI for assessment of bone density in patients with spinal degenerative disease. J Neurosurg Spine. 2022;36:414-421. doi:10.3171/2021.6.SPINE21666 [doi]
5. Jones BC, Lee H, Cheng CC, al Mukaddam M, Song HK, Snyder PJ, et al. MRI quantification of cortical bone porosity, mineralization, and morphologic structure in postmenopausal osteoporosis. Radiology. 2023;307:. doi:10.1148/radiol.221810 [doi]
6. Baron K, Neumayer B, Amerstorfer E, Scheurer E, Diwoky C, Stollberger R, et al. Time-dependent changes in T1 during fracture healing in juvenile rats: a quantitative MR approach. PLoS One. 2016;11:e0164284. doi:10.1371/journal.pone.0164284 [doi]
7. Ehresman J, Pennington Z, Schilling A, Lubelski D, Ahmed AK, Cottrill E, et al. Novel MRI-based score for assessment of bone density in operative spine patients. Spine J. 2020;20:556-562. doi:10.1016/j.spinee.2019.10.018 [doi]
8. Trattnig S, Millington SA, Szomolanyi P, Marlovits S. MR imaging of osteochondral grafts and autologous chondrocyte implantation. Eur Radiol. 2007;17:103-118. doi:10.1007/s00330-006-0333-z [doi]
9. Shayganfar A, Khodayi M, Ebrahimian S, Tabrizi Z. Quantitative diagnosis of osteoporosis using lumbar spine signal intensity in magnetic resonance imaging. Br J Radiol. 2019;92:1-5. doi:10.1259/bjr.20180774 [doi]

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http://echo.ismrm.org/p/ISMRM2026/407-04-006