Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
303-03-009 ISMRM Abstract

Tertiary Lymphoid Structures in Glioblastoma: Association with Multiparametric MRI Phenotypic Features and Patient Survival

Primary: Neuro
Secondary: Analysis Methods
303-03-009 · Advanced Tumor Imaging: Bridging Research and Clinical Practice · Monday, 11 May, 4:10 PM–6:00 PM · Auditorium 1
Keywords: Glioblastoma VASARI features Tumor microenvironment Survival analysis Neuroradiology
Accepted
Qing Zhou 1, Jinlin Zhou1
1Lanzhou University Second Hospital, Lanzhou, China
Presenting Author: Qing Zhou

Synopsis

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References

1. Asija S, Chatterjee A, Yadav S, et al.Combinatorial approaches to effective therapy in glioblastoma (GBM): Current status and what the future holds. Int Rev Immunol. 2022;41(6): 582–605.
2. Price M, Ballard C, Benedetti J, et al. CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States between 2017-2021. Neuro Oncol. 2024;26(Supplement_6): vi1–vi85.
3. Vaccaro A, de Alves PB, van de Walle T, Dimberg A. Tertiary Lymphoid Structures in Central Nervous System Disorders. Methods Mol Biol. 2025;2864: 21–42.
4. Sarti KG, Da SMT. Tertiary lymphoid structures ares the hubs of antitumour immunity. Nat Rev Cancer. 2023;23(12): 803.
5. Schumacher TN, Thommen DS. Tertiary lymphoid structures in cancer. Science. 2022;375(6576): eabf9419.
6. Lin WP, Li H, Sun ZJ. T cell exhaustion initiates tertiary lymphoid structures and the turbochargeds cancer -immuneity cycle. EBioMedicine. 2024;104: 105154.
7. Cui X, Gu X, Li D, et al. Tertiary lymphoid structures as a biomarkers in immunotherapy and beyond: Advancing towards clinical applications. Cancer Lett. 2025;613: 217491.
8. Sacli-Bilmez B, Firat Z, Topcuoglu OM, Yaltirik K, etTure U, Ozturk-Isik E. Identifying overall survival in 98 glioblastomas using VASARI features at 3T. Clin Imaging. 2023;93: 86–92.
9. Han Y, Wang YY, Yang Y, et al. Association between dichotomized VASARI features and overall survival in patients with glioblastoma patients: Aa single-institution propensity score matching analysis. Cancer Imaging. 2024;24(1): 109.
10. Klein C, Devi-Marulkar P, Dieu-Nosjean MC, et al. Advancement of tTechniques for precise visualization and quantification of tertiary lymphoid structure-associated immune cells in tissue samples. Methods Mol Biol. 2025;2864: 181–203.
11. Wegscheid ML, Jennings JW. VASARI Glioma Features: Insights into their impact and performance. Radiol Imaging Cancer. 2024;6(5): e249018.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/303-03-009