Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
560-02-012 ISMRM Abstract

QSM-Derived Limbic Iron Accumulation Predicts Cognitive and Epileptic Outcomes in Encephalitis

Primary: Neuro - Neuroinflammation
Secondary: Contrast Mechanisms - Susceptibility/QSM
560-02-012 · New Developments in QSM II · Wednesday, 13 May, 9:15 AM–10:10 AM · Digital Posters Row A
Keywords: Neuroinflammation White Matter Quantitative Susceptibility Mapping (QSM) Brain IRON Limbic encephalitis
Accepted
Yasmine Saad 1, Nader Gharbia2, Aymen Kammoun3, Meriem Mhiri1, Rihab Ben Dhia1, Najes Gouta1, Mahbouba Frih Ayed1
1Faculty of Medicine of Monastir, Tunisia
2Faculty of medicine of Sfax, Tunisia
3Faculty of Sciences of Monastir, Tunisia
Presenting Author: Yasmine Saad

Synopsis

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References

1. Ding JB, Dongas J, Hu K, Ding M. Autoimmune Limbic Encephalitis: A Review of Clinicoradiological Features and the Challenges of Diagnosis. Cureus. 2021 Aug 28;13(8):e17529. doi: 10.7759/cureus.17529. [doi]
2. Melzer N, Budde T, Stork O, Meuth SG. Limbic Encephalitis: Potential Impact of Adaptive Autoimmune Inflammation on Neuronal Circuits of the Amygdala. Front Neurol. 2015 Aug 3;6:171. doi: 10.3389/fneur.2015.00171. [doi]
3. Ravanfar P, Loi SM, Syeda WT, Van Rheenen TE, Bush AI, Desmond P, Cropley VL, Lane DJR, Opazo CM, Moffat BA, Velakoulis D, Pantelis C. Systematic Review: Quantitative Susceptibility Mapping (QSM) of Brain Iron Profile in Neurodegenerative Diseases. Front Neurosci. 2021 Feb 18;15:618435. doi: 10.3389/fnins.2021.618435. [doi]
4. Zheng W, Nichol H, Liu S, Cheng Y-C, Haacke EM. Measuring iron in the brain using quantitative susceptibility mapping and X-ray fluorescence imaging. Neuroimage. 2013;78:68–74. doi:10.1016/j.neuroimage.2013.04.022. [doi]
5. Gillen KM, Mubarak M, Park C, et al. QSM is an imaging biomarker for chronic glial activation in multiple sclerosis lesions. Ann Clin Transl Neurol. 2021;8(4):877–886. doi:10.1002/acn3.51338. [doi]
6. Kaunzner UW, Kang Y, Zhang S, et al. Quantitative susceptibility mapping identifies inflammation in a subset of chronic multiple sclerosis lesions. Brain. 2018;142:133–145. doi:10.1093/brain/awy296. [doi]
7. Stüber C, Pitt D, Wang Y. Iron in Multiple Sclerosis and Its Noninvasive Imaging with Quantitative Susceptibility Mapping. Int J Mol Sci. 2016;17(1):100. doi:10.3390/ijms17010100. [doi]
8. Wisnieff C, Ramanan S, Olesik J, et al. Quantitative susceptibility mapping (QSM) of white matter multiple sclerosis lesions: interpreting positive susceptibility and the presence of iron. Magn Reson Med. 2015;74(3):564–570. doi:10.1002/mrm.25420. [doi]
9. Cai Y, Yang Z. Ferroptosis and Its Role in Epilepsy. Front Cell Neurosci. 2021;15:696889. doi:10.3389/fncel.2021.696889. [doi]

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http://echo.ismrm.org/p/ISMRM2026/560-02-012