Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
431-01-008 / 431-01-008 ISMRM Abstract

Adaptive Data Acquisition Using Progressive Frequency Optimization and Deep Learning Reconstruction for Accelerated CEST MRI

Primary: Acquisition & Reconstruction - Image Reconstruction: AI
Secondary: Neuro - Tumors
431-01-008 · From Microstructure to Metabolism: Next-Generation MRI for Brain Tumors · Tuesday, 12 May, 8:20 AM–9:56 AM · Roof Terrace
431-01-008 · From Microstructure to Metabolism: Next-Generation MRI for Brain Tumors · Tuesday, 12 May, 8:20 AM–9:56 AM · Roof Terrace
Keywords: Deep learning reconstruction CEST MRI Accelerated CEST MRI Adaptive Data Acquisition Progressive Optimization
Accepted
Chathumi Samaraweera1, Mariano G Uberti2, Adarsha Bhattarai1, Anand Thiraviyam3, Afshin Salehi4, Aditya N Bade5, Yutong Liu 2,5, Dongming Peng1
1Department of Electrical and Computer Engineering, University of Nebraska-Lincoln, Lincoln, United States of America
2Department of Radiology, University of Nebraska Medical Center, Omaha, United States of America
3Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, United States of America
4Department of Neurosurgery, University of Nebraska Medical Center, Omaha, United States of America
5Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, United States of America
Presenting Author: Yutong Liu

Synopsis

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References

1. Simegn, G.L., Sun, P.Z., Zhou, J., Kim, M., Reddy, R., Zu, Z., Zaiss, M., Yadav, N.N., Edden, R.A., van Zijl, P.C. and Knutsson, L., (2025). Motion and magnetic field inhomogeneity correction techniques for chemical exchange saturation transfer (CEST) MRI: A contemporary review. NMR in Biomedicine, 38(1), p.e5294. doi: 10.1002/nbm.5294. [doi]
2. Jones, K.M., Pollard, A.C. and Pagel, M.D., (2018). Clinical applications of chemical exchange saturation transfer (CEST) MRI. Journal of Magnetic Resonance Imaging, 47(1), pp.11-27. doi: 10.1002/jmri.25838. [doi]
3. Rivlin, M., Perlman, O., & Navon, G. (2023). Metabolic brain imaging with glucosamine CEST MRI: In vivo characterization and first insights. Scientific Reports, 13(1), 22030. doi: 10.1038/s41598-023-48515-5 [doi]
4. Cheema, K., Han, P., Lee, H. L., Xie, Y., Christodoulou, A. G., & Li, D. (2025). Accelerated CEST imaging through deep learning quantification from reduced frequency offsets. Magnetic Resonance in Medicine. doi: 10.1002/mrm.30269 [doi]
5. Chen, L., Xu, H., Gong, T., Jin, J., Lin, L., Zhou, Y., & Chen, Z. (2024). Accelerating multipool CEST MRI of Parkinson’s disease using deep learning–based Z-spectral compressed sensing. Magnetic Resonance in Medicine, 92(6), 2616-2630. doi: 10.1002/mrm.30233. [doi]
6. Bhattarai A, Samaraweera C, Uberti M, Bade AN, Liu Y, Peng D. (2025) Advancing In Vivo Molecular Bioimaging With Optimal Frequency Offset Selection and Deep Learning Reconstruction for CEST MRI. IEEE Access. doi: 10.1109/access.2025.3571638. [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/431-01-008