Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
363-03-007 MRI in Clinical Practice Abstract

Diffusion Tensor Imaging of the Femoral Physis – reproducibility and biological correlates

Primary: Pediatrics
Secondary: Musculoskeletal
363-03-007 · MRI in Clinical Practice: Diagnostic Applications, Quantitative Imaging, and Emerging Techniques · Monday, 11 May, 1:50 PM–2:45 PM · Digital Posters Row D
Keywords: Pediatric Cartilage Musculoskeletal MRI Diffusion-Weighted Imaging Fractional anisotropy
Accepted
Francesca De Luca 1,2, Laura A Santos3, Camilo Perdomo-Luna3, Linnéa Corell4, Ferdinand von Walden4, Ola Kvist4,5
1Department of Neuroradiology, Karolinska University Hospital, Stockholm, Sweden
2Department of Clinical Neuroscience, Karolinska Institutet, Solna, Sweden
3Department of Radiology, Columbia University Irving Medical Center, New York, United States of America
4Department of Women’s and Children’s Health, Karolinska Institute, Stockholm, Sweden., Karolinska Institutet, Solna, Sweden
5Department of Pediatric Radiology, Columbia University Irving Medical Center, New York, United States of America
Presenting Author: Francesca De Luca

Synopsis

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References

1. Santos LA, Sullivan B, Kvist O, Jambawalikar S, Mostoufi-Moab S, Raya JM, Nguyen J, Marin D, Delgado J, Tokaria R, Nelson RR Jr, Kammen B, Jaramillo D. Diffusion tensor imaging of the physis: the ABC's. Pediatr Radiol. 2023 Nov;53(12):2355-2368. doi: 10.1007/s00247-023-05753-z. Epub 2023 Sep 2. PMID: 37658251; PMCID: PMC10859915. [doi] [pmid]
2. Jaimes C, Berman JI, Delgado J, Ho-Fung V, Jaramillo D. Diffusion-tensor imaging of the growing ends of long bones: pilot demonstration of columnar structure in the physes and metaphyses of the knee. Radiology. 2014;273(2):491–501. DOI: 10.1148/radiol.14132136 [doi]
3. Luo KL, Santos L, Tokaria R, Jambawalikar S, Duong PT, Raya JG, et al. Generalizing Diffusion Tensor Imaging of the Physis and Metaphysis. Journal of magnetic resonance imaging : JMRI. 2025;61(2):798–804. doi: 10.1002/jmri.29455. [doi]
4. Delgado J, Jaramillo D, Chauvin NA, Guo M, Stratton MS, Sweeney HE, Barrera CA, Mostoufi-Moab S. Evaluating growth failure with diffusion tensor imaging in pediatric survivors of high-risk neuroblastoma treated with high-dose cis-retinoic acid. Pediatr Radiol. 2019 Jul;49(8):1056-1065. doi: 10.1007/s00247-019-04409-1. Epub 2019 May 4. PMID: 31055614; PMCID: PMC6599475. [doi] [pmid]
5. Nilsson O, Baron J. Fundamental limits on longitudinal bone growth: growth plate senescence and epiphyseal fusion. Trends in endocrinology and metabolism: TEM. 2004;15(8):370–4. doi: 10.1016/j.tem.2004.08.004. [doi]
6. Kvist O, Dorniok T, Sanmartin Berglund J, Nilsson O, Flodmark CE, Diaz S. DTI assessment of the maturing growth plate of the knee in adolescents and young adults. Eur J Radiol. 2023 May;162:110759. doi: 10.1016/j.ejrad.2023.110759. Epub 2023 Mar 8. PMID: 36931119. [doi] [pmid]
7. Jaramillo D, Duong P, Nguyen JC, Mostoufi-Moab S, Nguyen MK, Moreau A, Barrera CA, Hong S, Raya JG. Diffusion Tensor Imaging of the Knee to Predict Childhood Growth. Radiology. 2022 Jun;303(3):655-663. doi: 10.1148/radiol.210484. Epub 2022 Mar 22. PMID: 35315716; PMCID: PMC9131176. [doi] [pmid]

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http://echo.ismrm.org/p/ISMRM2026/363-03-007