2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
452-02-003 / 452-02-003 ISMRM Abstract

Minimizing CSF Contamination in Velocity-selective Arterial Spin Labeling

Accepted
Zidong Yang1,2, Chenyang Zhao1,3, Fanhua Guo 1,3, Danny J Wang3,4,5
1Laboratory of FMRI Technology (LOFT), Mark & Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, United States of America
2Biomedical Engineering, University of Southern California, Los Angeles, United States of America
3University of Southern California, Los Angeles, United States of America
4Stevens Neuroimaging and Informatics Institute, United States of America
5Department of Neurology, University of Southern California, Los Angeles, United States of America
Presenting Author: Fanhua Guo

Synopsis

Motivation:
Goals:
Approach:
Results:
Preview figure: Minimizing CSF Contamination in Velocity-selective Arterial Spin Labeling
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References

1. Alexander, A. L., Tsuruda, J. S., & Parker, D. L. (1997). Elimination of eddy current artifacts in diffusion‐weighted echo‐planar images: The use of bipolar gradients. Magnetic Resonance in Medicine, 38(6), 1016–1021. https://doi.org/10.1002/mrm.1910380623 [doi]
2. Chen, C., Barnes, R. A., Bangen, K. J., Han, F., Pfeuffer, J., Wong, E. C., Liu, T. T., & Bolar, D. S. (2025). MVP‐VSASL: Measuring MicroVascular Pulsatility using velocity‐selective arterial spin labeling. Magnetic Resonance in Medicine, 93(4), 1516–1534. https://doi.org/10.1002/mrm.30370 [doi]
3. Guo, F., Zhao, C., Shou, Q., Jin, N., Jann, K., Shao, X., & Wang, D. J. (2025). Assessing cerebral microvascular volumetric with high-resolution 4D cerebral blood volume MRI at 7 T. Nature Cardiovascular Research, 4(10), 1424–1438. https://doi.org/10.1038/s44161-025-00722-1 [doi]
4. Guo, J., Meakin, J. A., Jezzard, P., & Wong, E. C. (2015). An optimized design to reduce eddy current sensitivity in velocity-selective arterial spin labeling using symmetric BIR-8 pulses: Reduced EC Sensitivity in VSASL Using Symmetric BIR-8 Pulses. Magnetic Resonance in Medicine, 73(3), 1085–1094. https://doi.org/10.1002/mrm.25227 [doi]
5. Qin, Q., Alsop, D. C., Bolar, D. S., Hernandez‐Garcia, L., Meakin, J., Liu, D., Nayak, K. S., Schmid, S., Van Osch, M. J. P., Wong, E. C., Woods, J. G., Zaharchuk, G., Zhao, M. Y., Zun, Z., Guo, J., & the ISMRMPerfusion Study Group. (2022). Velocity‐selective arterial spin labeling perfusion MRI: A review of the state of the art and recommendations for clinical implementation. Magnetic Resonance in Medicine, 88(4), 1528–1547. https://doi.org/10.1002/mrm.29371 [doi]

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