Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
301-02-008 ISMRM Abstract

In-vivo detection and treatment response assessment of rectal cancer using Field Cycling Imaging

Primary: Contrast Mechanisms - Novel Contrast Mechanisms
Secondary: Body - Digestive
301-02-008 · Advances in Rectum and Pelvis MRI · Monday, 11 May, 8:20 AM–10:10 AM · Hall 1A
Keywords: Treatment Response Rectal cancer 0.2T Field-Cycling Imaging (FCI) R1 Dispersion
Accepted
AMNAH S ALAMRI1,2,3, Nicholas Senn2,3, Leslie Samuel4,5, Rosalind Mitchell-Hay5,6, David Lurie2,5, George Ramsay5,6, Lionel M Broche 2
1Radiologic Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
2Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, United Kingdom
3Center for Adaptable MRI Technology (AMT Center), University of Aberdeen, Aberdeen, United Kingdom
4Department of Oncology, Aberdeen Royal Infirmary, Aberdeen, United Kingdom
5School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, United Kingdom
6Foresterhill Health Campus, Aberdeen Royal Infirmary, Aberdeen, United Kingdom
Presenting Author: Lionel M Broche

Synopsis

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References

1. Arnold, M., Sierra, M.S., Laversanne, M., Soerjomataram, I., Jemal, A., and Bray, F. (2017). Global patterns and trends in colorectal cancer incidence and mortality. Gut 66, 683–691. https://doi.org/10.1136/gutjnl-2015-310912. [doi]
2. Steele, R.M., Korb, J.-P., Ferrante, G., and Bubici, S. (2016). New applications and perspectives of fast field cycling NMR relaxometry. Magnetic Resonance in Chemistry 54, 502–509. https://doi.org/10.1002/mrc.4220. [doi]
3. Broche, L.M., Ross, P.J., Davies, G.R., MacLeod, M.-J., and Lurie, D.J. (2019). A whole-body Fast Field-Cycling scanner for clinical molecular imaging studies. Scientific Reports 9, 10402. https://doi.org/10.1038/s41598-019-46648-0. [doi]
4. Masiewicz, E., Ashcroft, G.P., Boddie, D., Dundas, S.R., Kruk, D., and Broche, L.M. (2020). Towards applying NMR relaxometry as a diagnostic tool for bone and soft tissue sarcomas: a pilot study. Scientific Reports 10, 14207. https://doi.org/10.1038/s41598-020-71067-x. [doi]
5. Ruggiero, M.R., Ait Itto, H., Baroni, S., Pierre, S., Boutonnat, J., Broche, L.M., Aime, S., Berger, F., Geninatti Crich, S., and Lahrech, H. (2022). Role of Transmembrane Water Exchange in Glioma Invasion/Migration: In Vivo Preclinical Study by Relaxometry at Very Low Magnetic Field. Cancers (Basel) 14. https://doi.org/10.3390/cancers14174180. [doi]
6. Ruggiero, M.R., Baroni, S., Bitonto, V., Ruiu, R., Rapisarda, S., Aime, S., and Geninatti Crich, S. (2021). Intracellular Water Lifetime as a Tumor Biomarker to Monitor Doxorubicin Treatment via FFC-Relaxometry in a Breast Cancer Model. Front. Oncol. 11, 778823. https://doi.org/10.3389/fonc.2021.778823. [doi]
7. Petit, M., Leclercq, M., Pierre, S., Ruggiero, M.R., El Atifi, M., Boutonnat, J., Fries, P.H., Berger, F., and Lahrech, H. (2022). Fast-field-cycling NMR at very low magnetic fields: water molecular dynamic biomarkers of glioma cell invasion and migration. NMR Biomed 35, e4677. https://doi.org/10.1002/nbm.4677. [doi]
8. Kołodziejski, K., Masiewicz, E., Alamri, A., Zampetoulas, V., Samuel, L., Murray, G., Lurie, D.J., Broche, L.M., and Kruk, D. (2024). Markers of low field NMR relaxation features of tissues. Sci Rep 14, 24901. https://doi.org/10.1038/s41598-024-74055-7. [doi]
9. Broche, L.M., Ross, P.J., Davies, G.R., and Lurie, D.J. (2017). Simple algorithm for the correction of MRI image artefacts due to random phase fluctuations. Magnetic Resonance Imaging 44, 55–59. https://doi.org/10.1016/j.mri.2017.07.023. [doi]

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http://echo.ismrm.org/p/ISMRM2026/301-02-008